Dimethyl chlorothiophosphate Chemical Properties

Boiling point:

66-67 °C16 mm Hg(lit.)

Density 

1.322 g/mL at 25 °C(lit.)

vapor pressure 

0.67 psi ( 20 °C)

refractive index 

n20/D 1.482(lit.)

Flash point:

221 °F

solubility 

Chloroform (Sparingly), Methanol (Slightly)

form 

Oil

color 

Colourless

Water Solubility 

slowly hydrolyzes

Stability:

Moisture Sensitive

CAS DataBase Reference

2524-03-0(CAS DataBase Reference)

NIST Chemistry Reference

Phosphorochloridothioic acid, o,o-dimethyl ester(2524-03-0)

EPA Substance Registry System

Dimethyl chlorothiophosphate (2524-03-0)

Safety Information

Hazard Codes 

T

Risk Statements 

23/24/25-34-23-21/22

Safety Statements 

23-26-36/37/39-45-24/25

RIDADR 

UN 2267 6.1/PG 2

WGK Germany 

3

RTECS 

TD1830000

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

29309099

Hazardous Substances Data

2524-03-0(Hazardous Substances Data)

Toxicity

mouse,LC50,inhalation,320mg/m3/2H (320mg/m3),"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 56, 1982.

MSDS

• Language:English Provider:O,O-Dimethyl phosphorochloridothioate
• Language:English Provider:SigmaAldrich

Dimethyl chlorothiophosphate Usage And Synthesis

Description

Dimethyl chlorothiophosphate is a colorless tolight amber, combustible liquid. Molecularweight= 160.56; Specific Gravity (H2O:1) 1.32 at 25℃;Boiling point = 6667℃ at 16 mmHg; Flashpoint= 104.8℃ (oc). Hazard Identification (based onNFPA-704 M Rating System): Health 3, Flammability 2,Reactivity 2. Insoluble in water.

Chemical Properties

clear colorless to light yellow liquid

Uses

Dimethyl chlorothiophosphate is used as an intermediate in the manufacture of insecticides, pesticides, fungicides, oil and gasoline additives, plasticizers, corrosion inhibitors, flame-retardants, and flotation agents.

Preparation

Dimethyl chlorothiophosphate is prepared by reaction of phosphorus pentasulfide & methyl alcohol followed by reaction of the resulting dimethyl phosphorodithioate with chlorine.

General Description

Dimethyl chlorothiophosphate is a colorless to light amber liquid. Used as a chemical intermediate for insecticides, pesticides, and fungicides; oil and gasoline additives; plasticizers; corrosion inhibitors; flame retardants; and flotation agents. Not registered as a pesticide in the U.S. (EPA, 1998)

Reactivity Profile

Organothiophosphates, such as Dimethyl chlorothiophosphate, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Health Hazard

Dimethyl chlorothiophosphate is a strong irritant to the eyes, skin, and mucous membranes.

Fire Hazard

Dimethyl chlorothiophosphate may burn but does not ignite readily. Dimethyl chlorothiophosphate may ignite combustibles (wood, paper, oil, etc.). When heated Dimethyl chlorothiophosphate emits very toxic fumes of chlorine containing compounds, phosphorus oxides, and sulfur oxides.

Flammability and Explosibility

Non flammable

Safety Profile

Poison by inhalation. Moderately toxic by ingestion and skin contact. Corrosive. When heated to decomposition it emits very toxic fumes of Cl-, POx, and SOx

Potential Exposure

This material is used as a chemicalintermediate for insecticides, pesticides, and fungicides; oiland gasoline additives; plasticizers; corrosion inhibitors;flame retardants; and flotation agents. It is not registered asa pesticide in the United States.[EP

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medical

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area. Metal containers involving the transfer ofthis chemical should be grounded and bonded. Where possible, automatically pump liquid from drums or other storagecontainers to process containers. Drums must be equippedwith self-closing valves, pressure vacuum bungs, and flamearresters. Sources of ignition, such as smoking and openflames, are prohibited where this chemical is used, handled,or stored in a manner that could create a potential fire orexplosion hazard. Wherever this chemical is used, handled,manufactured, or stored, use explosion-proof electricalequipment and fittings.

Shipping

Dimethyl thiophosphoryl chloride requires ashipping label of “POISONOUS/TOXIC MATERIALS/CORROSIVE.” This compound falls in DOT Hazard Class6.1 and Packing Group II.

Incompatibilities

Contact with oxidizers may cause therelease of phosphorous oxides. Contact with strong reducingagents, such as hydrides, may cause the formation of flammable and toxic phosphine gas.

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