Basic information Safety Supplier Related

QUIN 2-AM

Basic information Safety Supplier Related

QUIN 2-AM Basic information

Product Name:
QUIN 2-AM
Synonyms:
  • QUIN 2-AM
  • QUIN-2 TETRAACETOXYMETHYL ESTER
  • 2-[(2-AMINO-5-METHYLPHENOXY)METHYL]-6-METHOXY-8-AMINO-QUINOLINE-N,N,N',N'-TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL-ESTER)
  • 2-[[2-BIS(CARBOXYMETHYL)AMINO-5-METHYLPHENOXY]-METHYL]-6-METHOXY-8-BIS(CARBOXYMETHYL)AMINOQUINOLINE TETRAKIS(ACETOXYMETHYL) ESTER
  • quin2-acetoxymethylester
  • 2-[(2-amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-n,n,n',n'-tetraacetic acid tetrakis(acetoxymethyl ester)
  • 2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,Nμ,Nμ-tetraacetic acid tetrakis(acetoxymethyl ester), 2-{[2-Bis(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline tetrakis(acetoxymethyl) ester
  • 8-Amino-2-[(2-amino-5-methylphenoxy)-methyl]-6-methoxyquinoline-N,N,N',N'-tetraacetic acid
CAS:
83104-85-2
MF:
C38H43N3O18
MW:
829.76
Product Categories:
  • Quinoline
Mol File:
83104-85-2.mol
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QUIN 2-AM Chemical Properties

Density 
1.360
Flash point:
113 °C
storage temp. 
−20°C
solubility 
DMSO: soluble
λmax
348 nm
Biological Applications
Calcium indicator
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
1-8-10

MSDS

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QUIN 2-AM Usage And Synthesis

Description

Quin-2 AM is a cell-permeant acetoxymethyl ester of the high affinity fluorescent calcium indicator quin-2 . As quin-2 AM enters cells, it is hydrolyzed by intracellular esterases to produce quin-2. Quin-2 binds calcium with a Kd value of 115 nM. It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation and emission maxima for quin-2 are 339 and 492 nm, respectively.

Uses

2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester)

Uses

Fluorescent probe for measurement of calcium in biological systems and for selected divalent cations.

Uses

Quin 2-AM is a cell permeable fluorescent probe for Ca2+ that gives a large shift in the UV absorption spectrum and a 20-fold increase in fluorescence upon Ca2+ binding.

QUIN 2-AMSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
Beijing Ouhe Technology Co., Ltd
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010-82967028 13552068683
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Tianjin heowns Biochemical Technology Co., Ltd.
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400 638 7771
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885
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info@efebio.com
CONIER CHEM AND PHARMA LIMITED
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+8618523575427
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sales@conier.com