Methyl 1-methylpiperidine-3-carboxylate
Methyl 1-methylpiperidine-3-carboxylate Basic information
- Product Name:
- Methyl 1-methylpiperidine-3-carboxylate
- Synonyms:
-
- 1-methyl-3-piperidinecarboxylicacimethylester
- 1-methylnipecoticacidmethylester
- 1-methyl-nipecoticacimethylester
- dihydroarecoline
- methyln-methylnipecotate
- Methyl 1-methylpiperidine-3-carboxylate CAS no. 1690-72-8
- n-methyl-3-carbomethoxypiperidine
- 1-Methyl-3-Piperidinelarboxylate
- CAS:
- 1690-72-8
- MF:
- C8H15NO2
- MW:
- 157.21
- EINECS:
- 210-314-1
- Product Categories:
-
- Heterocyclic Compounds
- Mol File:
- 1690-72-8.mol
Methyl 1-methylpiperidine-3-carboxylate Chemical Properties
- Boiling point:
- bp12 83-84°
- Density
- 1.013±0.06 g/cm3(Predicted)
- refractive index
- nD25 1.4520
- storage temp.
- 2-8°C
- pka
- pKa (20°): 8.66
- CAS DataBase Reference
- 1690-72-8(CAS DataBase Reference)
Methyl 1-methylpiperidine-3-carboxylate Usage And Synthesis
Uses
Methyl 1-methylpiperidine-3-carboxylate belongs to the class of organic compounds known as piperidinecarboxylic acids. Piperidinecarboxylic acids are compounds containing a piperidine ring with a carboxylic acid group. Methyl 1-methylpiperidine-3-carboxylate is a strong basic compound (based on its pKa). It could be used to synthesize (1-methylpiperidin-3-yl)methanol. The specific steps are shown as follows: into a 500 mL round bottom flask containing a solution of methyl 1-methylpiperidine-3- carboxylate (12.0 g, 76 mmol) in tetrahydrofuran (500 mL) was added lithium aluminumhydride (4.3 g, 114 mmol) in portions at 0 °C. The reaction mixture was stirred at room temperature for 1 h. The reaction was quenched with methanol at 0 °C, and the precipitated solid was filtered through celite. The filtrate was concentrated and the crude was purified by flash chromatography eluting with methanol in dichloromethane (5-10percent) to afford (1-methylpiperidin-3-yl)methanol as a solid.
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Methyl 1-methylpiperidine-3-carboxylate(1690-72-8)Related Product Information
- Methyl N-methyl piperidine-4-carboxylate
- 1-BENZYL-3-METHOXYCARBONYL-4-PIPERIDONE
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- ETHYL 1-BENZYLPIPERIDINE-3-CARBOXYLATE
- N-Methyl-3-carbomethoxy-4-piperidone hydrochloride
- Ethyl 1-benzyl-4-oxo-3-piperidinecarboxylate hydrochloride
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- 3-METHYL-5-METHOXYCARBONYL-1-BENZYL-4-PIPERIDONE HYDROCHLORIDE, 99
- COCAINE PROPYL ESTER HCL
- COCAINE, LEVO-[BENZOYL-3,4-3H(N)]-
- ECGONINE METHYL ESTER HYDROCHLORIDE
- VOACANGINE
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