Ethyl 1-methylnipecotate Chemical Properties

Boiling point:

88-89 °C/11 mmHg (lit.)

Density 

0.954 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.451(lit.)

Flash point:

155 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

pka

8.56±0.10(Predicted)

color 

Colorless to Almost colorless

BRN 

123259

CAS DataBase Reference

5166-67-6(CAS DataBase Reference)

NIST Chemistry Reference

Ethyl 1-methylnipecotate(5166-67-6)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-37/39

WGK Germany 

3

F 

9-23

Hazard Note 

Irritant

HS Code 

29333990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Ethyl 1-methylnipecotate Usage And Synthesis

Chemical Properties

Clear colorless to pale yellow liquid

Uses

Reactant for:
N-demethylation of tertiary amines
Reverse cope elimination reactions
Regioselective oxidation
Synthesis of chelating agents
Sequential Michael-Michael-Dieckmann cyclizations

General Description

Enantiomeric discrimination has been investigated in ¹H and ¹³C NMR spectra of ethyl 1-methyl-3-piperidinecarboxylate in the presence of (-)-(18-crown-6)-2,3,11,12-tetracarboxylic acid.

Ethyl 1-methylnipecotate(5166-67-6)Related Product Information

• Ethylparaben
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• ISOXADIFEN-ETHYL
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