Basic information Safety Supplier Related

OPHIOBOLIN B

Basic information Safety Supplier Related

OPHIOBOLIN B Basic information

Product Name:
OPHIOBOLIN B
Synonyms:
  • OPHIOBOLIN B
  • 3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al
  • Cochliobolin B
  • Cochliobolin B, Zizanin B, Ophiobolsin A
  • Dicyclopenta[a,d]cyclooctene-4-carboxaldehyde, 7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1,7-dihydroxy-1,9a-dimethyl-3-oxo-, (1R,3aS,6aR,7S,9aR,10aS)-
  • Ophiobolin B (Cochliobolin B)
CAS:
5601-74-1
MF:
C25H38O4
MW:
402.57
Mol File:
5601-74-1.mol
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OPHIOBOLIN B Chemical Properties

storage temp. 
Store at -20°C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form 
White to off-white solid.
color 
White to off-white
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Safety Information

HS Code 
2932190090
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OPHIOBOLIN B Usage And Synthesis

Uses

Calmodulin is a calcium-sensing protein that regulates a wide array of proteins involved in diverse cellular functions. Ophiobolin B is a sesterterpenoid fungal phytotoxin that binds and irreversibly antagonizes calmodulin, producing cytotoxic and antimicrobial effects. It induces apoptosis in chronic lymphocytic leukemia cells with an LC50 value of 2 nM and in different zygomycetes with MIC values ranging from 25-50 μg/ml.[Cayman Chemical]

Uses

Ophiobolin B is a fungal phytotoxin and inhibits calmodulin (a protein involved in calcium regulation). Ophiobolin B also exhibit antibacterial and antitumor activities.

Uses

Ophiobolin B is a minor member of a class of phytotoxic metabolites produced by Bipolaris and other genera of plant pathogenic fungi. Ophiobolin B acts by inhibiting calmodulin action in calcium regulation.

OPHIOBOLIN BSupplier

Shanghai EFE Biological Technology Co., Ltd.
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