Triptonide Chemical Properties

Melting point:

251～252℃

Boiling point:

581.1±50.0 °C(Predicted)

Density 

1.48±0.1 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

solubility 

Dichloromethane (Slightly), Methanol (Slightly)

form 

Solid

color 

Off-White to Pale Beige

Triptonide Usage And Synthesis

Uses

Triptonide is a Triptolide (T815600) analogue used in the preparation of cytotoxic fluorinated Triptolide.

Definition

ChEBI: Triptonide is a diterpene triepoxide that is triptobenzene K in which the acylhydroquinone moiety has undergone oxidation to the corresponding triepoxyketone derivative. It has been isolated from the roots of Tripterygium wilfordii. It has a role as an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent. It is a cyclic ketone, an organic heteroheptacyclic compound, a diterpene triepoxide and a butenolide.

target

ERK | IL Receptor | GSK-3 | p38MAPK | Wnt/β-catenin

Triptonide(38647-11-9)Related Product Information

• Isopropyl alcohol
• Triptolide
• ISOPROPYL LAURATE
• Isopropyl acetate
• WILFORLIDE A
• Celastrol
• cicrotoic acid
• 1,2,3,4-DIEPOXYBUTANE
• 2-ETHOXYCYCLOHEXANONE
• Isobutyroin
• 1,3-Butadiene diepoxide
• 2,4-DIMETHYL-2-PENTENOIC ACID
• Methyl 1-cyclohexene-1-carboxylate
• CIS-4-TERT-BUTYLCYCLOHEXANOL
• Pinacol
• (-)-alpha-Terpineol
• Wilforlide
• (-)-DIHYDROCARVEOL