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Perindoprilat

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Perindoprilat Basic information

Product Name:
Perindoprilat
Synonyms:
  • PERINDOPRILAT
  • PERINDOPRILAT HYDRATE
  • (2s-(1(r*(r*)),2-alpha,3a-beta,7a-beta))-)
  • 1h-indole-2-carboxylicacid,octahydro-1-(2-((1-carboxybutyl)amino)-1-oxopropyl
  • (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-Carboxybutyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
  • (2S,3aS,7aS)-1-[(S)-2-[[(S)-1-Carboxybutyl]amino]-1-oxopropyl]hexahydroindoline-2-carboxylic acid
  • S-9780
  • Perindoprilat ,95%
CAS:
95153-31-4
MF:
C17H28N2O5
MW:
340.41
Product Categories:
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocycles
Mol File:
95153-31-4.mol
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Perindoprilat Chemical Properties

Melting point:
153-155°C
Boiling point:
568.1±45.0 °C(Predicted)
Density 
1.222±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
pka
2.27±0.20(Predicted)
CAS DataBase Reference
95153-31-4
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Safety Information

HS Code 
2933999552
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Perindoprilat Usage And Synthesis

Chemical Properties

White to Off-White Solid

Uses

An angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.

Uses

Perindoprilat is the active metabolite of perindopril, an inhibitor of angiotensin converting enzyme (ACE) that has efficacy against hypertension. Perindoprilat specifically and competitively inhibits ACE in vitro with IC50 values ranging between 1.5 and 3.2 nM. Elimination of perindoprilat is decreased in the elderly and in patients with heart or renal failure.[Cayman Chemical]

Uses

Perindoprilat is an angiotensin-converting enzyme (ACE) inhibitor and antihypertensive.

Perindoprilat Preparation Products And Raw materials

Raw materials

PerindoprilatSupplier

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