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(S)-(-)-Indoline-2-carboxylic acid

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(S)-(-)-Indoline-2-carboxylic acid Basic information

Product Name:
(S)-(-)-Indoline-2-carboxylic acid
Synonyms:
  • (R)-1H-INDOLE-2-CARBOXYLIC ACID
  • (R)-2,3-DIHYDRO-1H-INDOLE-2-CARBOXYLIC ACID
  • (R)-(+)-2,3-DIHYDROINDOLE-2-CARBOXYLIC ACID
  • Perindopril Intermediate
  • (2S)-indoline-2-carboxylic acid
  • (2S)-2,3-dihydro-1H-Indole-2-carboxylic acid
  • (S)-Indoline-2-Carboxylic
  • 1H-Indole-2-carboxylicacid,2,3-dihydro-,(2S)-(9CI)
CAS:
79815-20-6
MF:
C9H9NO2
MW:
163.17
EINECS:
410-860-2
Product Categories:
  • Heterocycle-Indole series
  • Chiral Compound
  • Indoles
  • Asymmetric Synthesis
  • Chiral Catalysts, Ligands, and Reagents
  • Proline-Based Organocatalysts
  • PYRROLE
  • Indoles and derivatives
  • pharmacetical
  • chiral
  • PERINDOPRIL
  • (intermediate of perindopril)
  • Pharmaceutical Intermediates
Mol File:
79815-20-6.mol
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(S)-(-)-Indoline-2-carboxylic acid Chemical Properties

Melting point:
177 °C (dec.)(lit.)
alpha 
-112.5 º (c=1, 1N HCl)
Boiling point:
290.25°C (rough estimate)
Density 
1.2021 (rough estimate)
refractive index 
-116 ° (C=1, 2mol/L HCl)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
Water Solubility 
Slightly soluble in water
pka
2.04±0.20(Predicted)
form 
Powder
color 
Beige to brown
optical activity
[α]20/D 114°, c = 1 in 1 M HCl
InChIKey
QNRXNRGSOJZINA-QMMMGPOBSA-N
CAS DataBase Reference
79815-20-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
43-48/22-62
Safety Statements 
22-25-26-36/37
WGK Germany 
2
HS Code 
29339900
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(S)-(-)-Indoline-2-carboxylic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

Catalyst for enantioselective cyclopropanations.

(S)-(-)-Indoline-2-carboxylic acid Preparation Products And Raw materials

Preparation Products

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