1,2-Decanediol Chemical Properties

Melting point:

48-50 °C (lit.)

Boiling point:

255 °C (lit.)

Density 

0.9418 (rough estimate)

vapor pressure 

0.004Pa at 20℃

refractive index 

1.4561 (estimate)

Flash point:

113 °C

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

pka

14.48±0.20(Predicted)

form 

Solid

color 

White to Off-White

Water Solubility 

579mg/L at 20℃

LogP

1.99 at 22.4℃

CAS DataBase Reference

1119-86-4(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

2

HS Code 

29053995

1,2-Decanediol Usage And Synthesis

Chemical Properties

White powder

Uses

1,2-Decanediol is a 1,2-alkanediol that is used as an antimicrobial agent in cosmetics. It also suppresses the fluidity of the hydrophilic and hydrophobic groups in the phospholipid membrane of liposomes. Preparation of 1-decene by deoxygenation of 1,2-decanediol with formic acid. It is used to Synthesis of EDOT-C8.

Definition

ChEBI: 1,2-Decanediol is a glycol that is decane bearing two hydroxy substituents located at positions 1 and 2. It has a role as an anti-inflammatory agent, an antioxidant and a human metabolite. It is a glycol and a volatile organic compound. It derives from a hydride of a decane.

Synthesis Reference(s)

Journal of the American Chemical Society, 98, p. 1986, 1976 DOI: 10.1021/ja00423a067
Synthesis, p. 45, 1989

Flammability and Explosibility

Non flammable

Synthesis

Synthesis of 1,2-decanediol: A homogeneous clear solution is prepared by adding 3 moles of acetone to 1 mole of a mixture of 1-nonene oxide and 1-decene oxide at room temperature. After 50 grams of 5% aqueous sulfuric acid to the solution, the acetone is evaporated off and the resulting solution is neutralized by adding an aqueous sodium hydroxide. The neutralized solution is extracted with pet ether and the extract dried over anhydrous magnesium sulfate. The pet ether is stripped off and a mixture of 1,2-nonanediol and 1,2-decanediol is obtained by distilling under vacuo.

1,2-Decanediol(1119-86-4)Related Product Information

• Ethylene glycol
• 1,4-Butanediol
• Polyethylene Glycol
• 1,3-Butanediol
• Estradiol
• Propylene glycol
• 1,3-Propanediol
• 2,2-Dimethyl-1,3-propanediol
• 1,5-Pentanediol
• 1,2-Pentanediol
• fluocinolone16,17-acetonide
• Triamcinolone
• 2-HydroxyMyristic Acid
• 1,2-Dodecanediol
• 2-HYDROXYDODECANOIC ACID
• Nystatin
• Estriol
• 1,2-Hexadecanediol