ZONIPORIDE
ZONIPORIDE Basic information
- Product Name:
- ZONIPORIDE
- Synonyms:
-
- N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine
- CP 597396
- ZONIPORIDE
- N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate
- Zoniporide hydrochloride hydrate
- 1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-
- N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide
- CAS:
- 241800-98-6
- MF:
- C17H16N6O
- MW:
- 320.35
- Mol File:
- 241800-98-6.mol
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ZONIPORIDE Chemical Properties
- Density
- 1.54
- storage temp.
- 2-8°C
- solubility
- H2O: soluble2mg/mL, clear (warmed)
- form
- powder
- pka
- 11.44±0.46(Predicted)
- color
- white to tan
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ZONIPORIDE Usage And Synthesis
Uses
Zoniporide hydrochloride hydrate has been used for the inhibition of sodium-hydrogen exchanger isoform 1 (NHE-1) in rat models. It has also been used in cytotoxicity assay and to study its effect on lymphocytic choriomeningitis virus multiplication.
Biochem/physiol Actions
Zoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM.
ZONIPORIDESupplier
Chengdu Forest Science and Technology Development Co., Ltd.
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- 18030648795 18030648795
- sales@cdforestchem.com
Sigma-Aldrich
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- 021-61415566 800-8193336
- orderCN@merckgroup.com
Shanghai Lollane Biological Technology Co.,Ltd.
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- 021-52996696，15000506266 15000506266
TargetMol Chemicals Inc.
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- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
BOC Sciences
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- info@bocsci.com