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(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL

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(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL Basic information

Product Name:
(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL
Synonyms:
  • (1R)-3-(Methylamino)-1-(2-thienyl)-1-propanol
  • (R)-3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol
  • (R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL
  • Duloxetine Impurity 17
  • (R)-3-Methylamino-1-(2-thienyl)-1-propanol
  • N-Methyl[(R)-3-hydroxy-3-(2-thienyl)propyl]amine
  • 2-Thiophenemethanol, α-[2-(methylamino)ethyl]-, (αR)
  • (1R)-3-(methylamino)-1-thiophen-2-ylpropan-1-ol
CAS:
116539-57-2
MF:
C8H13NOS
MW:
171.26
Mol File:
116539-57-2.mol
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(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL Chemical Properties

Boiling point:
294.3±35.0 °C(Predicted)
Density 
1.128
storage temp. 
2-8°C(protect from light)
pka
13.77±0.20(Predicted)
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(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL Usage And Synthesis

Uses

(R)-3-Methylamino-1-(2-thienyl)-1-propanol is a reactant used in the synthesis of enantiomerically pure Duloxetine (D721000), an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence.

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