QUINAPRILAT HYDRATE
QUINAPRILAT HYDRATE Basic information
- Product Name:
- QUINAPRILAT HYDRATE
- Synonyms:
-
- quinaprilat
- (3S)-2-[(S)-2-[[(S)-1-Carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
- (3S)-2-[(S)-2-[[(S)-1-Carboxy-3-phenylpropyl]amino]propionyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
- Quinapril Related Compound B (50 mg) (3-Isoquinolinecarboxylic acid, 2-[2-[(1-carboxy-3-phenylpropyl)amino]-1-oxopropyl]-1,2,3,4-tetrahydro-,[3S-[2[R*(R*)],3R*]]-)
- Quinapril USP Related CoMpound B
- Quinapril Related CoMpound B
- (3S)-2-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid
- CI-92
- CAS:
- 82768-85-2
- MF:
- C23H26N2O5
- MW:
- 410.46
- Product Categories:
-
- Various Metabolites and Impurities
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 82768-85-2.mol
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QUINAPRILAT HYDRATE Chemical Properties
- Melting point:
- 166-1680C
- alpha
- D23 +20.9° (c = 1 in methanol)
- Boiling point:
- 674.5±55.0 °C(Predicted)
- Density
- 1.289±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- DMSO: ≥23mg/mL
- form
- powder
- pka
- 2.19±0.10(Predicted)
- color
- white to tan
- optical activity
- [α]/D +16 to +23 (C=1, MeOH)
- CAS DataBase Reference
- 82768-85-2
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QUINAPRILAT HYDRATE Usage And Synthesis
Chemical Properties
Crystalline Solid
Uses
Quinaprilat (Quinapril EP Impurity C) is a metabolite of Quinapril, an angiotensin converting enzyme (ACE) inhibitor.
Definition
ChEBI: Quinaprilat is a dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a vasodilator agent. It is a dicarboxylic acid, a member of isoquinolines and a tertiary carboxamide.
QUINAPRILAT HYDRATESupplier
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QUINAPRILAT HYDRATE(82768-85-2)Related Product Information
- [2H5]-Quinapril
- QUINAPRIL RELATED COMPOUND A (50 MG) (ETHYL[3S-[2(R*),3A,11A BETA]]-1,3,4,6,11,11A-HEXAHYDRO-3-METHYL-1,4-DIOXO-ALPHA-(2-PHENY-LETHYL)-2H-PYRAZINO[1,2-B]ISOQUINOLINE-2-ACETATE)
- CarboxylicAcidPhenylMethylEsterHydrochloride,QuinaprilHcl
- [3S-[2[R*(R*)],3R*]]-2-[2-[[1-(Ethoxycarbonyl)-3-phenylpropyl]aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic Acid Ethyl Ester (2Z)-2-Butenedioate
- Quinapril hydrochloride EP impurity G
- Quinapril
- (3S)-3,4-Dihydro-2-[(2S)-2-[[(1S)-1-[(1-Methylethoxy)carbonyl]-3-phenylpropyl]aMino]-1-oxopropyl]-3(1H)-isoquinolinecarboxylic Acid
- IBBLRJGOOANPTQ-GOMJJGCLSA-N
- Quinapril Cyclohexyl Analog
- Quinaprilat-D5
- QUINAPRILAT HYDRATE
- MOEXIPRILAT HYDRATE
- Quinapril hydrochloride
- Moexipril
- (S)-2-[(S)-2-((S)-1-Ethoxycarbonyl-3-phenylpropylamino)propionyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid benzyl ester
- Quinapril benzyl ester maleate
- MOEXIPRILAT-D5
- QUINAPRIL-D5, HYDROCHLORIDE