(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one Chemical Properties

Boiling point:

642.9±55.0 °C(Predicted)

Density 

1.251±0.06 g/cm3(Predicted)

pka

9.72±0.30(Predicted)

(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one Usage And Synthesis

Uses

Di-desfluoro Ezetimibe is a dehalogenated impurities observed in halogen-containing pharmaceuticals. Also, it is a related compound to Ezetimibe (E975000), which is an antihyperlipoproteinemic. A cholesterol absorption inhibitor.

(3R,4S)-3-((S)-3-hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one(1251741-03-3)Related Product Information

• NA
• Ezetimibe Impurity 70
• Ezetimibe Impurity 50
• (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide
• Ezetimibe Impurity 11
• (S)-3-((2R,5R)-5-(4-fluorophenyl)-2-((S)-(4-fluorophenylaMino)(4-hydroxyphenyl)Methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
• Ezetimibe Impurity
• (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-(4-fluorophenylaMino)(4-hydroxyphenyl)Methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
• Ezetimibe Impurity 43
• 4-[[(4-Fluorophenyl)imino]methyl]-phenol
• (S)-3-((2R,5R)-5-(4-fluorophenyl)-5-hydroxy-2-((S)-hydroxy(4-hydroxyphenyl)methyl)pentanoyl)-4-phenyloxazolidin-2-one
• (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
• EzetiMibe Dehydoxy IMpurity
• (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone
• Ezetimibe Impurity 36
• Ezetimibe Impurity 35
• EzetiMibe ring-opening dehydrate iMpurity
• (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one