2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Chemical Properties

Melting point:

298-310 °C

Boiling point:

1203.6±65.0 °C(Predicted)

Density 

1.40±0.1 g/cm3(Predicted)

refractive index 

163 ° (C=1, H2O)

storage temp. 

Sealed in dry,Room Temperature

solubility 

H₂O: soluble

form 

Crystalline Powder

pka

11.63±0.70(Predicted)

color 

White to faintly yellow

optical activity

[α]20/D +158±3°, c = 10% in H2O

Water Solubility 

212.6g/L(cold water)

BRN 

1679144

InChIKey

QGKBSGBYSPTPKJ-UZMKXNTCSA-N

CAS DataBase Reference

51166-71-3

Safety Information

Safety Statements 

24/25

WGK Germany 

3

RTECS 

GU2293500

HS Code 

29400090

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Usage And Synthesis

Chemical Properties

White to faintly yellow crystalline powder

Uses

Induces the release of cholesterol from cholesterol-rich lipid rafts located on the surface of cells, making it a good agent for removing cholesterol from processed foods

Uses

Reactant involved in:

• Physicochemical studies of inclusion complexes
• Probing diffusion and single molecule interactions with reconstituted membrane proteins
• Interactions with micelles causing micellar rupture
• Studying cellular transport, used as a cell penetration enhancer
• Physicochemical and biopharmaceutical improvement of drugs particularly with solubilization and stability
• Interactions with cholesterol

General Description

Heptakis(2,6-di-O-methyl)-β-cyclodextrin is a hydrophilic derivative of cyclodextrin that possesses the ability to effectively dissolve lipophilic drugs like steroid hormones, vitamins A, E, and K, etc. It can be utilized to increase the dissolution and bioavailability of weakly water-soluble pharmaceutical compounds.

2,6-DI-O-METHYL-BETA-CYCLODEXTRIN(51166-71-3)Related Product Information

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