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2,6-DI-O-METHYL-BETA-CYCLODEXTRIN

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2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Basic information

Product Name:
2,6-DI-O-METHYL-BETA-CYCLODEXTRIN
Synonyms:
  • DIMETHYL BETA-CYCLODEXTRIN
  • DIMEB
  • HEPTAKIS(2,6-DI-O-METHYL)-BETA-CYCLODEXTRIN
  • 2,6-DI-O-METHYL-BETA-CYCLODEXTRIN
  • Dimethyl-beta-cyclodextrin, methylated beta-cyclodextrins
  • Di-O-methyl-β-cyclodextrin
  • Methyl-beta-cyclodextrin (2,6-Di-O-methyl- and partially 2,3,6-Tri-O-methyl- mixture)
  • 2,6-Dimethyl-b-cyclodextrin
CAS:
51166-71-3
MF:
C56H98O35
MW:
1331.36
EINECS:
1312995-182-4
Product Categories:
  • Biochemistry
  • Cyclodextrins
  • Functional Materials
  • Macrocycles for Host-Guest Chemistry
  • Oligosaccharides
  • Sugars
Mol File:
51166-71-3.mol
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2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Chemical Properties

Melting point:
298-310 °C
Boiling point:
1203.6±65.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
refractive index 
163 ° (C=1, H2O)
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: soluble
form 
Crystalline Powder
pka
11.63±0.70(Predicted)
color 
White to faintly yellow
optical activity
[α]20/D +158±3°, c = 10% in H2O
Water Solubility 
212.6g/L(cold water)
BRN 
1679144
InChIKey
QGKBSGBYSPTPKJ-UZMKXNTCSA-N
CAS DataBase Reference
51166-71-3
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
GU2293500
HS Code 
29400090

MSDS

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2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Usage And Synthesis

Chemical Properties

White to faintly yellow crystalline powder

Uses

Induces the release of cholesterol from cholesterol-rich lipid rafts located on the surface of cells, making it a good agent for removing cholesterol from processed foods

Uses

Reactant involved in:

  • Physicochemical studies of inclusion complexes
  • Probing diffusion and single molecule interactions with reconstituted membrane proteins
  • Interactions with micelles causing micellar rupture
  • Studying cellular transport, used as a cell penetration enhancer
  • Physicochemical and biopharmaceutical improvement of drugs particularly with solubilization and stability
  • Interactions with cholesterol

General Description

Heptakis(2,6-di-O-methyl)-β-cyclodextrin is a hydrophilic derivative of cyclodextrin that possesses the ability to effectively dissolve lipophilic drugs like steroid hormones, vitamins A, E, and K, etc. It can be utilized to increase the dissolution and bioavailability of weakly water-soluble pharmaceutical compounds.

2,6-DI-O-METHYL-BETA-CYCLODEXTRINSupplier

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