DESETHYL HYDROXY CHLOROQUINE
DESETHYL HYDROXY CHLOROQUINE Basic information
- Product Name:
- DESETHYL HYDROXY CHLOROQUINE
- Synonyms:
-
- 2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]amino]ethanol
- 2-[4-[(7-chloroquinolin-4-yl)amino]pentylamino]ethanol
- Hydroxychloroquine?EP?Impurity?C/Desethyl?Hydroxychloroquine/Cletoquine/2-[[(4RS)-4-[(7-Chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol
- DESETHYL HYDROXY CHLOROQUINE
- cletoquine
- Hydroxychloroquine Sulfate Impurity 3（Hydroxychloroquine Sulfate EP Impurity C）
- Hydroxychloroquine Sulfate EP Impurity C (Desethyl Hydroxy Chloroquine)
- Desethyl Hydroxy Chloroquine DiHCl
- CAS:
- 4298-15-1
- MF:
- C16H22ClN3O
- MW:
- 307.82
- EINECS:
- 1308068-626-2
- Product Categories:
-
- Metabolite
- API
- Mol File:
- 4298-15-1.mol
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DESETHYL HYDROXY CHLOROQUINE Chemical Properties
- Melting point:
- 112-115°C
- Boiling point:
- 514.7±50.0 °C(Predicted)
- Density
- 1.212±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
- pka
- 14.80±0.10(Predicted)
- form
- Solid
- color
- Off-White to Yellow
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20)
- InChIKey
- XFICNUNWUREFDP-UHFFFAOYSA-N
- SMILES
- C(O)CNCCCC(NC1C2C(N=CC=1)=CC(Cl)=CC=2)C
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DESETHYL HYDROXY CHLOROQUINE Usage And Synthesis
Uses
Cletoquine is a metabolite of Hydroxychloroquine (H916900), an antimalarial; antirheumatic; lupus erythematosus suppressant.
in vivo
Hydroxychloroquine (5 mg/kg intravenously) is administered to BALB/c mice for blood and tissue to determine the content of Cletoquine (Desethylhydroxychloroquine). The tissue to blood concentration ratio (Kp) is ≥1, indicating accumulation of Cletoquine in tissues. The Cletoquine Kp ratio for the various tissues are observed in the descending order of liver (114.3)>kidney (24.4)>spleen (19.3)>lungs (16.5)>heart (5.5)[3].
DESETHYL HYDROXY CHLOROQUINESupplier
Zhengzhou Ruike Biochemical Technology Co., Ltd. Gold
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- 18521304688
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Hubei Kele Fine Chemical Co., Ltd Gold
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- 027-59101668 19945030958
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Wuhan Augda Biotechnology Co., Ltd Gold
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- 15071299552
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Hefei fuya biotechnology co. LTD Gold
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- 18096409024
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Shanghai YuZn Pharm. Technology Co.,Ltd. Gold
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- 15921286451; 15921286451
- 2010681527@qq.com
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DESETHYL HYDROXY CHLOROQUINE(4298-15-1)Related Product Information
- 4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol
- Hydroxychloroquine O-Sulfate
- Linagliptin Impurity D
- Linagliptin Impurity K
- Linagliptin iMpurity G
- 8-Bromo-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione
- Tert-butyl((3s)-1-(7-(but-2-yn-1-yl)-3-Methyl-1-((4-Methylquinazolin-2-yl)Methyl)-2,6-dioxo-2,3,4,5,6,7-hexahydro-1h-purin-8-yl)piperidin-3-yl)carbaMate
- Linagliptin iMpurity E
- Hydroxychloroquine Sulfate EP Impurity A
- Linagliptin Impurity F
- BISDESETHYL CHLOROQUINE
- Hydroxychloroquine sulfate
- Hydroxychloroquine
- CHLOROQUINE
- DESETHYL HYDROXY CHLOROQUINE
- DESETHYL CHLOROQUINE
- 4-(4-AMINOBUT-1-YL)AMINOQUINOLINE
- 4-(4-AMINOBUTYL)AMINO-7-CHLOROQUINOLINE