DESETHYL CHLOROQUINE
DESETHYL CHLOROQUINE Basic information
- Product Name:
- DESETHYL CHLOROQUINE
- Synonyms:
-
- DESETHYL CHLOROQUINE
- Deethylchloroquine
- Desethyl Chloroquine DiHBr (Hydroxychloroquine Sulfate EP Impurity D DiHBr)
- Hydroxychloroquine Sulfate EP Impurity D DiHBr
- Chloroquine Impurity 1（Desethyl Chloroquine）
- Hydroxychloroquine Sulfate Impurity 4（Hydroxychloroquine Sulfate EP Impurity D）
- Hydroxychloroquine Impurity 9 2HBr
- Monodeethylchloroquine
- CAS:
- 1476-52-4
- MF:
- C16H22ClN3
- MW:
- 291.82
- Product Categories:
-
- Metabolite
- Various Metabolites and Impurities
- Heterocycles
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 1476-52-4.mol
DESETHYL CHLOROQUINE Chemical Properties
- Melting point:
- 94-97?C
- Boiling point:
- 173-175 °C(Press: 0.05 Torr)
- Density
- 1.138±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
- form
- Solid
- pka
- 10.62±0.19(Predicted)
- color
- Pale Yellow to Dark Yellow
- biological source
- synthetic
DESETHYL CHLOROQUINE Usage And Synthesis
Chemical Properties
DESETHYL CHLOROQUINE is Tan Solid
Uses
Desethyl Chloroquine is the major product of the stereoselective human metabolism of Chloroquine, used for the therapy and prevention of malaria. It is a COVID19-related research product.
Definition
ChEBI: Desethylchloroquine is an aminoquinoline.
in vivo
Intraperitoneal injections of Chloroquine are administered to wild-type and Huntington's disease (Q175/Q175) mice. LC-MS/MS is used to compare the levels Chloroquine and its metabolites in blood, brain and muscle tissue. Concentrations of Chloroquine are lower (5-15M), but more stable in brain tissue compared to blood or muscle between 4 and 24 hours after the last dose. Levels of the active Chloroquine metabolite Desethyl chloroquine decreased in muscle and blood over the 24 hour post-injection period, while brain Desethyl chloroquine levels are lower and rose slightly over the same time frame[3].
IC 50
Plasmodium; TLRs
DESETHYL CHLOROQUINESupplier
- Tel
- 18210857532
- jkinfo@jkchemical.com
- Tel
- 021-50135380
- shchemsky@sina.com
- Tel
- 86-21-60936353
- Tel
- 0755-4000505016 13380397412
- 3001272453@qq.com
- Tel
- 13901585132
- 799750417@qq.com
DESETHYL CHLOROQUINE(1476-52-4)Related Product Information
- Desethyl Chloroquine-d4
- LABOTEST-BB LT00452833
- CHLOROQUINE
- DESETHYL HYDROXY CHLOROQUINE
- 6-Amino-7-chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline di phosphate
- Mepacrine hydrochloride
- DESETHYL CHLOROQUINE
- Hydroxychloroquine
- ICR 386
- QUINACRINE MUSTARD DIHYDROCHLORIDE
- Chloroquine diphosphate
- Aminoquinol
- Hydroxychloroquine sulfate
- CHLOROQUINE-[3H(G)]
- 7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)-6-nitroquinoline di phosphate
- Chloroquine sulfate