ChemicalBook > Product Catalog > Organic Chemistry > Amides > Sulfonic acids amino compound > 2-HYDROXYSACLOFEN
2-HYDROXYSACLOFEN
2-HYDROXYSACLOFEN Basic information
- Product Name:
- 2-HYDROXYSACLOFEN
- Synonyms:
-
- HYDROXYSACLOFEN
- 3-amino-2-(4-chlorophenyl)-2-hydroxy-*propanesulf
- 2-HYDROXYSACLOFEN GABA(B) RECEPTOR ANTA
- 3-AMINO-2-(4-CHLOROPHENYL)-2-HYDROXY-PRO PANESULFON
- 2-HYDROXYSACLOFEN, >99%
- 3-Amino-2-(4-chlorophenyl)-2-hydroxypropane-1-sulfonic acid
- 3-Amino-2-hydroxy-2-(4-chlorophenyl)propane-1-sulfonic acid
- 2-Oh-saclofen
- CAS:
- 117354-64-0
- MF:
- C9H12ClNO4S
- MW:
- 265.71
- Product Categories:
-
- GABA/Glycine receptor
- Mol File:
- 117354-64-0.mol
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2-HYDROXYSACLOFEN Chemical Properties
- Melting point:
- 267-269 °C
- RTECS
- DA0359200
- storage temp.
- 2-8°C
- solubility
- H2O: 1 mg/mL
- form
- solid
- color
- white
- Water Solubility
- Soluble in water at 1mg/ml. Also soluble in DMSO, 0.1M HCl and methanol
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Safety Information
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-27-36/37/39-45
- RIDADR
- UN 1759 8/PG 3
- WGK Germany
- 3
- HazardClass
- 8
MSDS
- Language:English Provider:SigmaAldrich
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2-HYDROXYSACLOFEN Usage And Synthesis
Uses
2-Hydroxysaclofen is a GABA-B receptor antagonist in the ventral tegmental area and may play a role in the mechanisms of cocaine usage. Affects specific acute nicotine responses in mice, abolishing hypolocomotion and increasing antinociception.
Definition
ChEBI: 3-amino-2-(4-chlorophenyl)-2-hydroxy-1-propanesulfonic acid is an organochlorine compound.
Biological Activity
Selective antagonist at GABA B receptors.
storage
Store at RT
2-HYDROXYSACLOFENSupplier
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