ERIOCITRIN
ERIOCITRIN Basic information
- Product Name:
- ERIOCITRIN
- Synonyms:
-
- (S)-3',4',5,7-TETRAHYDROXYFLAVANONE-7-[6-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]
- ERIOCITRIN
- ERIODICTYL-7-RUTINOSIDE
- ERIODICTYOL-7-O-RUTINOSIDE
- ERIODICTYOL-7-RUTINOSIDE
- (s)-3',4',5,7-tetrahydroxyflavanone-7-[6-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]
- (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxan-2-yl]oxy-chroman-4-one
- ERIOCITRIN(SH)
- CAS:
- 13463-28-0
- MF:
- C27H32O15
- MW:
- 596.53
- EINECS:
- 236-668-7
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- Flavanones
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 13463-28-0.mol
ERIOCITRIN Chemical Properties
- Melting point:
- 161-190°C
- Boiling point:
- 956.9±65.0 °C(Predicted)
- Density
- 1.77
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO (Slightly), Methanol
- pka
- 7.15±0.40(Predicted)
- form
- Solid
- color
- Dark Beige to Very Dark Beige
- BRN
- 1304401
- LogP
- 1.470 (est)
- CAS DataBase Reference
- 13463-28-0(CAS DataBase Reference)
MSDS
- Language:English Provider:SigmaAldrich
ERIOCITRIN Usage And Synthesis
Description
Eriocitrin is a flavonoid originally isolated from lemon peel that has antioxidant and enzyme inhibitory activity. Eriocitrin inhibits lipid peroxidation in a cell-free assay when used at a concentration of 10 μM and enhances the effect of α-tocopherol on lipid peroxidation. It also decreases thiobarbituric acid reactive substances (TBARS) in rat plasma when administered at a dose of 75 μmol/kg, indicating a reduction in lipid peroxidation. Eriocitrin prevents acute exercise-induced increases in TBARS, Nε-(hexanoyl)lysine (HEL), o,o-dityrosine (DT), and nitrotyrosine (NT; ) in rat liver when administered at a dose of 600 mg/kg prior to exercise. It is also an inhibitor of monoamine oxidase A (MAO-A) and MAO-B (IC50s = 86.5 and 164 μM, respectively, for human recombinant receptors).
Chemical Properties
solid
Uses
Eriocitrin is one of the main flavonoids in citrus limon byproduct dried powder (CBP) that exhibits antioxidant activity.
Definition
ChEBI: A disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage
target
LDL | ATP synthase
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