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ERIOCITRIN

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ERIOCITRIN Basic information

Product Name:
ERIOCITRIN
Synonyms:
  • (S)-3',4',5,7-TETRAHYDROXYFLAVANONE-7-[6-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]
  • ERIOCITRIN
  • ERIODICTYL-7-RUTINOSIDE
  • ERIODICTYOL-7-O-RUTINOSIDE
  • ERIODICTYOL-7-RUTINOSIDE
  • (s)-3',4',5,7-tetrahydroxyflavanone-7-[6-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]
  • (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxan-2-yl]oxy-chroman-4-one
  • ERIOCITRIN(SH)
CAS:
13463-28-0
MF:
C27H32O15
MW:
596.53
EINECS:
236-668-7
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • Flavanones
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
13463-28-0.mol
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ERIOCITRIN Chemical Properties

Melting point:
161-190°C
Boiling point:
956.9±65.0 °C(Predicted)
Density 
1.77
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol
pka
7.15±0.40(Predicted)
color 
Dark Beige to Very Dark Beige
BRN 
1304401
LogP
1.470 (est)
CAS DataBase Reference
13463-28-0(CAS DataBase Reference)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
10-21
HS Code 
29389090

MSDS

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ERIOCITRIN Usage And Synthesis

Description

Eriocitrin is a flavonoid originally isolated from lemon peel that has antioxidant and enzyme inhibitory activity. Eriocitrin inhibits lipid peroxidation in a cell-free assay when used at a concentration of 10 μM and enhances the effect of α-tocopherol on lipid peroxidation. It also decreases thiobarbituric acid reactive substances (TBARS) in rat plasma when administered at a dose of 75 μmol/kg, indicating a reduction in lipid peroxidation. Eriocitrin prevents acute exercise-induced increases in TBARS, Nε-(hexanoyl)lysine (HEL), o,o-dityrosine (DT), and nitrotyrosine (NT; ) in rat liver when administered at a dose of 600 mg/kg prior to exercise. It is also an inhibitor of monoamine oxidase A (MAO-A) and MAO-B (IC50s = 86.5 and 164 μM, respectively, for human recombinant receptors).

Chemical Properties

solid

Uses

Eriocitrin is one of the main flavonoids in citrus limon byproduct dried powder (CBP) that exhibits antioxidant activity.

Definition

ChEBI: A disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage

target

LDL | ATP synthase

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