Uridine, 4',5'-didehydro-2',5'-dideoxy- Chemical Properties

Density 

1.47±0.1 g/cm3(Predicted)

pka

9.34±0.10(Predicted)

Uridine, 4',5'-didehydro-2',5'-dideoxy- Usage And Synthesis

Uses

4′,5′-Didehydro-2′,5′-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

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