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H2N-PEG1-CH2COOtBu

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H2N-PEG1-CH2COOtBu Basic information

Product Name:
H2N-PEG1-CH2COOtBu
Synonyms:
  • H2N-PEG1-CH2COOtBu
  • tert-Butyl 2-(2-aminoethoxy)acetate
  • NH2-PEG1-C1-Boc
  • tert-Butyl 2-(2-aminoethoxy)acetate hemioxalate
  • Acetic acid, 2-(2-aminoethoxy)-, 1,1-dimethylethyl ester
  • tert-butyl(2-amino-ethoxy)acetate
  • NH2-PEG1-CH2COOtBu
  • 2-(2-Aminoethoxy)acetic acid tert-butyl ester
CAS:
1155811-37-2
MF:
C8H17NO3
MW:
175.23
Mol File:
1155811-37-2.mol
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H2N-PEG1-CH2COOtBu Chemical Properties

Boiling point:
247.0±15.0 °C(Predicted)
Density 
1.006±0.06 g/cm3(Predicted)
pka
8.52±0.10(Predicted)
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H2N-PEG1-CH2COOtBu Usage And Synthesis

Uses

NH2-PEG1-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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