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Difluoro Atorvastatin Acetonide tert-Butyl Ester

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Difluoro Atorvastatin Acetonide tert-Butyl Ester Basic information

Product Name:
Difluoro Atorvastatin Acetonide tert-Butyl Ester
Synonyms:
  • tert-butyl 2-((4R,6R)-6-(2-(2,3-bis(4-fluorophenyl)-5-isopropyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
  • Atorvastatin Impurity Ⅳ
  • Atorvastatin Impurity 41
  • Atorvastatin calcium-20
  • Atorvastatin impurity 19/Difluoro Atorvastatin Acetonide tert-Butyl Ester/(4R,6R)-6-[2-[2,3-Bis(4-fluorophenyl)-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-Dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
  • 1,3-Dioxane-4-acetic acid, 6-[2-[2,3-bis(4-fluorophenyl)-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
  • Atorvastatin calcium impurity 28
  • tert-Butyl (4R,6R)-6-[2-[2,3-Bis(4-fluorophenyl)-5-isopropyl-4-(phenylcarbamoyl)-1-pyrrolyl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:
693793-87-2
MF:
C40H46F2N2O5
MW:
672.8
Mol File:
693793-87-2.mol
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Difluoro Atorvastatin Acetonide tert-Butyl Ester Chemical Properties

Melting point:
173 - 175°C
Boiling point:
677.4±55.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
13.38±0.70(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
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Difluoro Atorvastatin Acetonide tert-Butyl Ester Usage And Synthesis

Uses

Difluoro Atorvastatin Acetonide tert-Butyl Ester is a useful synthetic intermediate in the synthesis of Difluoro Atorvastatin (D445660); an Atorvastatin impurity.

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