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3-Oxo Atorvastatin tert-Butyl Ester

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3-Oxo Atorvastatin tert-Butyl Ester Basic information

Product Name:
3-Oxo Atorvastatin tert-Butyl Ester
Synonyms:
  • 3-Oxo Atorvastatin tert-Butyl Ester
  • 1,1-dimethylethyl (R)-7-(2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrol-1-yl)-5-hydroxy-3-oxo-1-heptanoate
  • Atorvastatin Impurity 88
  • Atorvastatin Impurity 99
  • 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-δ-hydroxy-5-(1-methylethyl)-β-oxo-3-phenyl-4-[(phenylamino)carbonyl]-, 1,1-dimethylethyl ester, (δR)-
  • (R)-tert-butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxy-3-oxoheptanoate
CAS:
134394-98-2
MF:
C37H41FN2O5
MW:
612.7302432
Mol File:
134394-98-2.mol
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3-Oxo Atorvastatin tert-Butyl Ester Chemical Properties

Boiling point:
702.4±60.0 °C(Predicted)
Density 
1.16±0.1 g/cm3(Predicted)
pka
10.39±0.46(Predicted)
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3-Oxo Atorvastatin tert-Butyl Ester Usage And Synthesis

Uses

3-Oxo Atorvastatin tert-Butyl Ester is a Boc-protected oxo-derivative of Atorvastatin (A791750, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin can also lower both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

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