Basic information Safety Supplier Related

2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide

Basic information Safety Supplier Related

2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Basic information

Product Name:
2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide
Synonyms:
  • 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide
  • Atorvastatin Impurity 24
  • 2-(1,2-bis(4-fluorophenyl)-2-oxoethyl)-4-methyl-3-oxo-N-phenylpentanamide
  • Atorvastatin Impurity 5
  • Atorvastatin impurity 18/2-(1,2-bis(4-fluorophenyl)-2-oxoethyl)-4-methyl-3-oxo-N- phenylpentanamide
  • (3R,5R)-tert-butyl 7-(2-(2-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
  • Atorvastatin Calcium Hydrate impurity 37
  • 2-(1,2-bis(4-fluorophenyl)
CAS:
693793-82-7
MF:
C26H23F2NO3
MW:
435.46
Mol File:
693793-82-7.mol
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2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Chemical Properties

Boiling point:
633.7±55.0 °C(Predicted)
Density 
1.248±0.06 g/cm3(Predicted)
pka
11.49±0.59(Predicted)
InChI
InChI=1S/C26H23F2NO3/c1-16(2)24(30)23(26(32)29-21-6-4-3-5-7-21)22(17-8-12-19(27)13-9-17)25(31)18-10-14-20(28)15-11-18/h3-16,22-23H,1-2H3,(H,29,32)
InChIKey
KUEDWDDLRXOHDM-UHFFFAOYSA-N
SMILES
C(NC1=CC=CC=C1)(=O)C(C(C1=CC=C(F)C=C1)C(C1=CC=C(F)C=C1)=O)C(=O)C(C)C
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2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Usage And Synthesis

Uses

4-Fluoro-β-(4-fluorophenyl)-α-(2-methyl-1-oxopropyl)-γ-oxo-N-phenylbenzenebutanamide is an intermediate in the synthesis of Difluoro Atorvastatin Acetonide tert-Butyl Ester (D445455), a useful synthetic intermediate in the synthesis of Difluoro Atorvastatin (D445660); an Atorvastatin impurity.

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