3-Maleimidobenzoic acid N-hydroxysuccinimide ester
3-Maleimidobenzoic acid N-hydroxysuccinimide ester Basic information
- Product Name:
- 3-Maleimidobenzoic acid N-hydroxysuccinimide ester
- Synonyms:
-
- MBS
- 3-MALEIMIDOBENZOIC ACID N-HYDROXYSUCCINIMIDE ESTER
- 3-MALEIMIDOBENZOIC ACID N-SUCCINIMIDYL ESTER
- 3-(2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-yl)benzoic acid 2,5-dioxopyrrolidine-1-yl ester
- 3-(2,5-Dioxo-3-pyrroline-1-yl)benzoic acid succinimidyl ester
- 3-(Maleimide-N-yl)benzoic acid succinimidyl ester
- 3-[(2,5-Dioxo-2,5-dihydro-1H-pyrrole)-1-yl]benzoic acid 2,5-dioxo-1-pyrrolidinyl ester
- Succinimidylmaleimidobenzoate
- CAS:
- 58626-38-3
- MF:
- C15H10N2O6
- MW:
- 314.25
- EINECS:
- 261-368-8
- Product Categories:
-
- Nitric Oxide Reagents
- N-Substituted Maleimides
- N-Substituted Maleimides, Succinimides & Phthalimides
- N-Substituted Succinimides
- Cross Linking Reagents
- Maleimide Derivatives
- Cross Linking Reagents,Maleimide Derivatives
- MTS & Sulfhydryl Active Reagents
- Heterobifunctional Crosslinker
- heteroXlink
- Mol File:
- 58626-38-3.mol
3-Maleimidobenzoic acid N-hydroxysuccinimide ester Chemical Properties
- Melting point:
- 175-177 °C(lit.)
- Boiling point:
- 524.5±52.0 °C(Predicted)
- Density
- 1.59±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- ethyl acetate or DMF: ≤20 mg/mL may require addition of solvent to coupling buffer to at least 5% to maintain solubility
- form
- crystalline
- pka
- -2.63±0.20(Predicted)
- color
- White to Almost white
- Sensitive
- Moisture & Light Sensitive
- BRN
- 1505254
- InChIKey
- LLXVXPPXELIDGQ-UHFFFAOYSA-N
- CAS DataBase Reference
- 58626-38-3(CAS DataBase Reference)
MSDS
- Language:English Provider:SigmaAldrich
3-Maleimidobenzoic acid N-hydroxysuccinimide ester Usage And Synthesis
Description
MBS is a heterobifunction crosslinker that contains a maleimide group which is reactive towards sulfhydryls and an NHS ester, useful for targeting amine groups.
Chemical Properties
Crystalline
Uses
N-Succinimidyl 3-maleimidobenzoate is useful for forming enzyme immunoconjugates. It has a 9.9 Angstrom spacer arm. Heterobifunctional crosslinking reagent reactive toward primary amine and sulfhydryl. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates
Uses
3-Maleimidobenzoic acid N-hydroxysuccinimide ester is a heterobifunctional coupling reagent useful for forming enzyme immunoconjugates. The reactive groups are the NHS ester and maeimide.
Biochem/physiol Actions
3-Maleimidobenzoic acid N-hydroxysuccinimide is used as a fixative for the preservation of pollen tube F-actin distribution. It imposes less damage when used on pollen tubes.
3-Maleimidobenzoic acid N-hydroxysuccinimide esterSupplier
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3-Maleimidobenzoic acid N-hydroxysuccinimide ester(58626-38-3)Related Product Information
- O-Phthalimide
- Bismaleimide
- N-Chlorosuccinimide
- Tris(trimethylsilyl)phosphate
- Succinimide
- Methyl acrylate
- BUTYL OLEATE
- Ethyl 2-(Chlorosulfonyl)acetate
- N-Hydroxysuccinimide
- Maleimide
- 3-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-BENZOIC ACID
- DIALIFOS
- Maleimido-3,5-disuccinimidyl isophthalate
- M-MALEIMIDOBENZOYL-N-HYDROXYSULFOSUCCINIMIDE ESTER
- 3-Maleimidobenzoic acid N-hydroxysuccinimide ester
- N-SUCCINIMIDYL-3,5-DIMALEIMIDOPHENYL BENZOATE