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4-NITROBENZHYDRAZIDE

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4-NITROBENZHYDRAZIDE Basic information

Product Name:
4-NITROBENZHYDRAZIDE
Synonyms:
  • 4-Nitrobenzoic hydrazide 98%
  • ρ-Nitrobenzoyl hydrazine
  • P-NITROBENZHYDRAZIDE
  • P-NITROBENZOHYDRAZIDE
  • Benzoicacid,4-nitro-,hydrazide
  • p-Nitrobenzoic acid hydrazide
  • p-Nitrobenzoic hydrazide
  • p-nitrobenzoicacidhydrazide
CAS:
636-97-5
MF:
C7H7N3O3
MW:
181.15
EINECS:
211-271-1
Product Categories:
  • Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes
  • Carbonyl Compounds
  • Hydrazides
  • Organic Building Blocks
  • Hydrazide
  • Miscellaneous
  • Nitro
Mol File:
636-97-5.mol
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4-NITROBENZHYDRAZIDE Chemical Properties

Melting point:
210-214 °C
Boiling point:
292.97°C (rough estimate)
Density 
1.3539 (rough estimate)
refractive index 
1.5860 (estimate)
solubility 
acetone: soluble0.5g/10 mL, clear, yellow
pka
2.77, 11.17(at 25℃)
form 
crystals
color 
Yellow
PH Range
Colorless (8.2) to yellow (9.5)
λmax
267nm
BRN 
519882
Major Application
corrosion inhibitor, disinfectant, cosmetics, paints toothpaste, mouthwash, antifungal agent, inhibit fibrosis, antituberculosis agent
CAS DataBase Reference
636-97-5(CAS DataBase Reference)
EPA Substance Registry System
4-Nitrobenzoylhydrazine (636-97-5)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-20/21/22
Safety Statements 
36/37/39-26-37/39
WGK Germany 
3
RTECS 
DH5670000
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29280000

MSDS

  • Language:English Provider:ACROS
  • Language:English Provider:ALFA
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4-NITROBENZHYDRAZIDE Usage And Synthesis

Synthesis

Dissolve 218 g of p-nitrobenzyl acetate in 500 ml of hot methanol, stir, and slowly add 380 g of 15% sodium hydroxide solution. After the addition was completed, it was placed for 5 minutes, and then poured into ice water to precipitate a precipitate. The filtered precipitate was decolorized with activated carbon in hot water, and recrystallized to give p-nitrobenzoicacidhydrazide 110-121 g .

Chemical Properties

yellow crystalline powder

Uses

4-Nitrobenzoic hydrazide has been used as internal standard in determination of isoniazid in human plasma by LC-MS/MS method.

Definition

ChEBI: A C-nitro compound in which the nitro group is substituted into the 4-position of benzohydrazide.

4-NITROBENZHYDRAZIDESupplier

Jinan Liheng Biotechnology Co., Ltd.
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0531-18763987518 18763987518
Email
levi@lihengpharm.com