BISPYRAZOLONE Chemical Properties

Melting point:

355 °C

Boiling point:

481.12°C (rough estimate)

Density 

1.31

refractive index 

1.6620 (estimate)

storage temp. 

Refrigerator

solubility 

formic acid: 50 mg/mL, clear, yellow

pka

2.15±0.70(Predicted)

form 

crystalline

color 

tan

BRN 

572787

CAS DataBase Reference

7477-67-0(CAS DataBase Reference)

EPA Substance Registry System

[4,4'-Bi-3H-pyrazole]-3,3'-dione, 2,2',4,4'-tetrahydro-5,5'-dimethyl-2,2'-diphenyl- (7477-67-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

43

Safety Statements 

36/37

WGK Germany 

3

TSCA 

Yes

HS Code 

29331990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

BISPYRAZOLONE Usage And Synthesis

Chemical Properties

off-white to cream-yellowish crystalline powder

Uses

It is applied as a reagent for the detection and determination of cyanide. It is also used in an experimental procedure, done in order to remove linamarin in starch from cassava roots, by using plant cell wall-degrading enzymes, xylanase and cellulase. It was also used for spectrophotometric determination and quantization of urea in urine samples. It is also used in assay of cyanogenic compounds and determination of ammonia.

Uses

Bispyrazolone is an impurity of Edaravone (E335000).

BISPYRAZOLONE(7477-67-0)Related Product Information

• 1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one
• 1H-Pyrazole, 5-methoxy-3-methyl-1-phenyl-
• Acetyl ketene
• Edaravone Impurity 14
• Edaravone Impurity 26
• Edaravone Impurity 5
• Edaravone Impurity 8
• ethyl 3-acetoxy-2-butenoate
• Edaravone Impurity 15
• Edaravone Impurity 19
• 1H-Pyrazole,3-ethoxy-5-methyl-1-phenyl-(9CI)
• Edaravone Impurity 6
• NSC4751
• Edaravone
• 5-Oxo-1-phenyl-2-pyrazolin-3-carboxylic acid
• benzenediazonium chloride
• 4,5-Dihydro-α,3-diMethyl-5-oxo-1-phenyl-α-sulfo-1H-pyrazole-4-acetic Acid
• Edaravone Impurity 11