Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate Chemical Properties

Melting point:

93-95 °C

Boiling point:

93-95 °C/5 mmHg (lit.)

alpha 

14 º (neat)

Density 

1.19 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.452

Flash point:

>110°C

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)

pka

13.23±0.20(Predicted)

form 

Oil

Specific Gravity

1.190

color 

Clear Colourless

optical activity

[α]23/D +14°, neat

InChIKey

ZAJNMXDBJKCCAT-RXMQYKEDSA-N

CAS DataBase Reference

90866-33-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

41

Safety Statements 

26-36-36/39

RIDADR 

2810

WGK Germany 

3

HazardClass 

6.1

PackingGroup 

III

HS Code 

29181990

MSDS

• Language:English Provider:4-Chloro-3-hydroxybutyric acid ethyl ester
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate is a chiral building block that can be used:

• To prepare allyl stannane, a precursor for the total synthesis of macrolide iriomoteolide-1b.
• As a starting material for the synthesis of a chiral g-αmino acid fragment, which in turn is used to prepare the immunosuppressive agent FR252921.

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate(90866-33-4)Related Product Information

• 4-Hydroxybenzoic acid
• Ethyl 3-hydroxybutyrate
• Ethyl acrylate
• Glycolic acid
• Ethyl acetate
• HYDROXYAPATITE TYPE I
• Ethyl isobutyrate
• Ethylparaben
• Epichlorohydrin
• Tris(trimethylsilyl)phosphate
• 2,3,4-Trihydroxybenzoic acid
• Ethyl butyrate
• 4-Cyanophenol
• Hydroxy silicone oil
• Ethanol
• (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER
• Ethyl S-4-chloro-3-hydroxybutyrate
• Difluorochloromethane