9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALT
9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALT Basic information
- Product Name:
- 9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALT
- Synonyms:
-
- 11,15-Dihydroxy-16,16-dimethyl-9-methyleneprosta-5,13-dien-1-oic acid monopotassium salt, (5Z,11alpha,13E,15R)-
- Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-methylene-, monopotassium salt, (5Z,11alpha,13E,15R)-
- AWJFDDHQLBRQDS-PWOMVKEHSA-N
- U-46785B
- METENPROST POTASSIUM
- 9-METHYLENE-11ALPHA,15R-DIHYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID, POTASSIUM SALT
- 9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALT
- Meteneprost potassium
- CAS:
- 122576-55-0
- MF:
- C23H39KO4
- MW:
- 418.66
- Mol File:
- 122576-55-0.mol
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9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALT Chemical Properties
- solubility
- DMF: >2 mg/ml; DMSO: >12.5 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >50 mg/ml
- form
- A crystalline solid
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9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALT Usage And Synthesis
Uses
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (metenprost) is a potent analog of PGE2 with an extended half-life in vivo. In combination with various other PG derivatives, metenprost results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of metenprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This PG mixture is ineffective on monkeys in their third trimester of pregnancy. Metenprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.
9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALTSupplier
Shanghai Yifei Biotechnology Co. , Ltd.
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TargetMol Chemicals Inc.
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Cayman Chemical Company
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Santa Cruz Biotechnology Inc
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