2,4,5-Trichloropyrimidine Chemical Properties

Boiling point:

84°C 1mm

Density 

1.6001 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.574(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

form 

clear liquid

pka

-4.26±0.29(Predicted)

color 

Colorless to Light orange to Yellow

Water Solubility 

Not miscible or difficult to mix in water.

BRN 

4449

InChI

InChI=1S/C4HCl3N2/c5-2-1-8-4(7)9-3(2)6/h1H

InChIKey

GIKMWFAAEIACRF-UHFFFAOYSA-N

SMILES

C1(Cl)=NC=C(Cl)C(Cl)=N1

CAS DataBase Reference

5750-76-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

3267

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

8

PackingGroup 

III

HS Code 

29335990

MSDS

• Language:English Provider:2,4,5-Trichloropyrimidine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2,4,5-Trichloropyrimidine Usage And Synthesis

Chemical Properties

Colorless to pale yellow liquid

Uses

2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. Also used in the synthesis of EGFR inhibitors.

2,4,5-Trichloropyrimidine(5750-76-5)Related Product Information

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