((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one
((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one Basic information
- Product Name:
- ((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one
- Synonyms:
-
- (1R)-(-)-2-AZABICYCLO[2.2.1]HEPT-5-EN-3-ONE
- (1R,4S)-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
- (-)-VINCE'S LACTAM
- (1R)-(-)-2-AZABICYCLO(2.2.1)HEPT-5-EN-3- ONE, 98+% (99% EE/HPLC)
- (-)-Vince lactam
- (1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one,98%,> 95%ee
- (1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one ,98%
- (-)-2-Azabicyclo[2.2.1]hept-5-en-3-one, > 95% ee
- CAS:
- 79200-56-9
- MF:
- C6H7NO
- MW:
- 109.13
- EINECS:
- 418-530-1
- Product Categories:
-
- Chiral Reagents
- Heterocycles
- Antiviral Agents
- Chiral Building Blocks
- Intermediates
- Heterocycle-other series
- Lactams
- Organic Building Blocks
- Mol File:
- 79200-56-9.mol
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((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one Chemical Properties
- Melting point:
- 94-97 °C(lit.)
- Boiling point:
- 319.3±0.0 °C(Predicted)
- Density
- 1.198±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
- pka
- 15.48±0.20(Predicted)
- form
- Crystals or Crystalline Powder
- color
- Off-white to beige
- optical activity
- [α]20/D 565°, c = 1 in chloroform
- BRN
- 4230721
- InChIKey
- DDUFYKNOXPZZIW-UHNVWZDZSA-N
- CAS DataBase Reference
- 79200-56-9
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-41-43
- Safety Statements
- 24-26-37/39
- WGK Germany
- 1
- HS Code
- 29337900
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
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((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one Usage And Synthesis
Chemical Properties
OFF-WHITE TO BEIGE CRYSTALS OR CRYSTALLINE POWDER
Uses
(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one can be used as a precursor to prepare:
- Amino-peramivir, a potent neuraminidase inhibitor.
- Five membered analogs of 4-amino-5-halopentanoic acids as potential GABA aminotransferase (GABA-AT) inactivators.
Uses
((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one is an abacavir intermediate. It is used as an intermediate in the synthesis of carbocyclic sugar amines, carbanucleosides, and carbocyclic dinucleotide analogues.
General Description
(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one is a bicyclic γ-lactam.
((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one Preparation Products And Raw materials
Raw materials
EtanolEthyl acetateTetrahydrofuranPotassium carbonateAmmonium hydroxideParaformaldehydeIsopropyl ethertert-Butyl methyl ether1，3-CyclopentadieneVinyl acetateLipaseCyanogen bromideSodium p-toluenesulfonate10,11-Dimethoxystrychnine
Preparation Products
((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-oneSupplier
Anhui Dali Biotechnology Co. , Ltd. Gold
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- 0563-6601666; 15705632007
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Shanghai Bioman Pharma Limited Gold
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- 21-33738120 15000110506
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Shanghai Tube Pharmaceutical Co., Ltd. Gold
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- 021-54338626 18017892860
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Wuhu Nuowei Chemical Technology Co., Ltd Gold
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- 0553-2911116 18055326116
- sales@nuowei-chem.com
FUJIAN WELIKE PHARMA CO.,LTD. Gold
- Tel
- 0598-5883999 18505989636
- wcq@welikepharma.com