Basic information Description Safety Supplier Related
ChemicalBook >  Product Catalog >  Biochemical Engineering >  Saccharides >  Monosaccharide >  D-(+)-Glucono-1,5-lactone

D-(+)-Glucono-1,5-lactone

Basic information Description Safety Supplier Related

D-(+)-Glucono-1,5-lactone Basic information

Product Name:
D-(+)-Glucono-1,5-lactone
Synonyms:
  • Gluconolactone - CAS 90-80-2 - Calbiochem
  • Glucono Delta Lactone, Glucono Delta Lactone powder
  • Cagliflozin Impurity 8
  • delta-Gluconolactone in stock GMP Factory
  • 1,2,3,4,5-PENTAHYDROXYCAPROIC ACID DELTA-LACTONE
  • DELTA-GLUCURONOLACTONE
  • DELTA-GLUCONOLACTONE
  • D(+)-DEXTRONIC ACID DELTA-LACTONE
CAS:
90-80-2
MF:
C6H10O6
MW:
178.14
EINECS:
202-016-5
Product Categories:
  • food additive
  • stabilizer
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Food additives
  • Biochemistry
  • Glucose
  • Sugar Acids
  • Sugars
  • Dextrins、Sugar & Carbohydrates
  • bc0001
Mol File:
90-80-2.mol
More
Less

D-(+)-Glucono-1,5-lactone Chemical Properties

Melting point:
160 °C (dec.)(lit.)
alpha 
65 º (c=1,H2O)
Boiling point:
230.35°C (rough estimate)
Density 
0.6
refractive index 
63.5 ° (C=10, H2O)
storage temp. 
Sealed in dry,Room Temperature
solubility 
590g/l Hydrolysis
form 
Crystalline Powder
pka
12.06±0.60(Predicted)
color 
White to off-white
Odor
wh. cryst. powd., pract. odorless
PH
3.6 (10g/l, H2O, 20℃)
Water Solubility 
500 g/L (20 ºC)
Merck 
14,4457
BRN 
83286
LogP
-2.38
CAS DataBase Reference
90-80-2(CAS DataBase Reference)
NIST Chemistry Reference
D-Gluconic acid, «delta»-lactone(90-80-2)
EPA Substance Registry System
.delta.-Gluconolactone (90-80-2)
More
Less

Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
21-36/38-46-62-63
Safety Statements 
24/25-53-36/37-26-25
WGK Germany 
3
RTECS 
LZ5184000
21
TSCA 
Yes
HS Code 
29322090
Hazardous Substances Data
90-80-2(Hazardous Substances Data)

MSDS

More
Less

D-(+)-Glucono-1,5-lactone Usage And Synthesis

Description

Delta-Gluconolactone (GDL) is a lactone of the D-gluconate. It is a natural constituent of many foods. It can be found in honey, fruit juices, wine and many-fermented products1-3. It is used as a food additive with the E number E575 used as a sequestrant, an acidifier (it lower the pH and also help preserve the food from deterioration by enzymes and organisms), or a curing, pickling, or leavening agent. GDL has been marketed for use in feta cheese. GDL is neutral, but hydrolyses in water to gluconic acid that is acidic, adding a tangy taste to foods, though it has roughly a third of the sourness of citric acid. It can be used as nutritional supplement in beverage such as in Instant Drinks, Syrups, RTD Tea and Coffee, Sports and Energy Drinks, Waters.

Description

Glucono delta-lactone (C6H10O6), molecular weight 178.14, is an inner ester of gluconic acid. Commonly named gluconolactone, other synonyms include D-gluconic acid delta-lactone, D-glucono- 1, 5-lactone, and D-delta-gluconolactone. Some of its earliest uses as a food ingredient were as a flavoring (e.g., sherbets) and to reduce fat absorption in doughnuts and cones. Glucono deltalactone tastes sweet initially and has a slightly acid-aftertaste.

Chemical Properties

Powder

Uses

Geogard(R)Ultra is a synergistic blend of gluconolactone and sodium benzoate. This blend provides broad spectrum protection against product spoilage in a variety of personal care formulations. Product Data Sheet

Uses

A lactone (cyclic ester) of D-gluconic acid used as a used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent.

Uses

a product of the oxidation of glucose by glucose oxidase

Uses

gluconolactone is used in cosmetics for its anti-acne properties. It can also help improve skin hydration given its water-binding ability. In addition, formulators may select gluconolactone for its action as a product stabilizer (chelating agent). Some studies indicate potential free-radical scavenging capacities as well. These properties would make it particularly relevant for use in making anti-aging, moisturizing, and possibly sun care products.

Uses

(GDL) An acidulant. It hydrolyzes to form gluconic acid in water solution and thereby creates the desired pH. The rate of acid formation is affected by temperature, concentration, and the pH of the solution. It has low acid release at room temperature and accelerated conversion into gluconic acid at high temperatures. It is readily soluble with a solubility of 59 g in 100 ml of water at 20°C. It functions as a leavening agent, acidulant, curing and pickling agent, and pH control agent. It is comparatively less tart/sour than other food acids. It is used in baked goods, fish products, desserts, and dressings.

Uses

D-glucono-1,5-lactone is the lactone derivative of D-gluconic acid. D-glucono-1,5-lactone is widely used as a food additive to achieve a curing, pickling or leavening effect.

Uses

Component of many cleaning cmpds because of the sequestering ability of the gluconate radical which remains active in alk solutions; in the dairy industry to prevent milkstone; in breweries to prevent beerstone; as latent acid catalyst for acid colloid resins, particularly in textile printing; as a coagulant for tofu.

Preparation

Glucono delta-lactone is prepared commercially by the oxidation of glucose with bromine water.

Definition

ChEBI: D-glucono-1,5-lactone is an aldono-1,5-lactone obtained from D-gluconic acid. It has a role as an animal metabolite and a mouse metabolite. It is a gluconolactone and an aldono-1,5-lactone. It is functionally related to a D-gluconic acid.

General Description

Gluconolactone is a non-toxic component of the skin. It has anti-oxidant and free radical scavenging effects. Gluconolactone has antiaging and skin-firming properties. It acts as a?β-glucosidase inhibitor. Gluconolactone stimulates cellulase gene expression.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Glucono-d-lactone increased the doubling time and activated enzymes involved in the oxidative pentose phosphate pathway of Saccharomyces cerevisiae.

Safety Profile

Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Crystallise Dglucono-lactone from ethylene glycol monomethyl ether and dry for 1hour at 110o. It can be freed from other sugars via a column of Celite and charcoal (750g of each, 90 x 7.5cm) which is washed with 0.01N formic acid until the pH of the wash is equal to that of the entering acid. The lactone is applied in H2O and eluted with 0.01N formic acid (7L), then eluted with 7.5% EtOH/0.01N formic acid (8L), then 15% EtOH/0.01N formic acid (8L) which removes pentose and isomaltose (the optical rotation of the eluates are used for sugar detection) and finally elution with aqueous formic acid provides glucolactone which is obtained by evaporating or freeze drying. Its solubility in H2O is 60% and 1% in EtOH. A solution in H2O is slightly acidic, and the lactone dissolves in an equivalent of aqueous NaOH to form sodium D-gluconate [527-07-1] M 218.1, m 2002 0 6o(dec), [ ] D 25 +12o (c 10, H2O), pK2 5 3.6. [cf p 553, Smith & Whelan Biochemical Preparations 10 127 1963, Beilstein 3 IV 1255.]

D-(+)-Glucono-1,5-lactoneSupplier

Wisdom Drugs Co., Ltd. Gold
Tel
18261161868
Email
527536256@qq.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
PharmaBlock Sciences (Nanjing),Inc.
Tel
400-0255188 4000255188
Email
sales@pharmablock.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Email
market03@meryer.com
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com