EC 1.1.1.47 Chemical Properties

storage temp. 

-20°C

form 

powder

color 

white

biological source

bacterial (Pseudomonas spp.)

Specific Activity

≥200U/mg

EPA Substance Registry System

Dehydrogenase, glucose (9028-53-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

10-21

HS Code 

35079090

MSDS

• Language:English Provider:SigmaAldrich

EC 1.1.1.47 Usage And Synthesis

Uses

Diagnostics and cofactor regeneration of NAD(P)H in reductive processes

General Description

This product has been enhanced for energy efficiency and waste prevention when used in biofuel cell research.

Biochem/physiol Actions

In bacteria, the membrane integrated glucose dehydrogenase catalyses the conversion of glucose to gluconic acid. It uses pyrroloquinoline quinone as a coenzyme. The intracellular glucose dehydrogenase lack this cofactor. It is a nicotinamide adenine dinucleotide (NADH) dependent enzyme.

Description

UGDH Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 533 amino acids (1-494 a.a.) and having a molecular mass of 59.5 kDa. The UGDH is fused to a 39 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

UGDH is part of the UDP-glucose/GDP-mannose dehydrogenase family and is a widely expressed enzyme localized in the liver. UGDH transfers UDP-glucose to UDP-glucuronate and thus takes part in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated products are ordinary molecules of the extracellular matrix and participate in signal transduction, cell migration, and cancer growth and metastasis.

EC 1.1.1.47(9028-53-9)Related Product Information

• CALCIUM GLUCONATE MONOHYDRATE
• Zinc gluconate
• Potassium gluconate
• D-(+)-Glucono-1,5-lactone
• Copper(II) gluconate
• Ferrous gluconate
• Glucose oxidase
• Ribonuclease A
• Magnesium gluconate
• Manganese gluconate
• Sodium gluconate
• Chlorhexidine digluconate
• 6-PHOSPHOGLUCONIC DEHYDROGENASE
• GLUCOSE-6-PHOSPHATE DEHYDROGENASE
• GLUCOSE DEHYDROGENASE NADP DEPENDENT
• EC 1.1.1.22
• D-Glucose Dehydogenase
• ANTI-GLUCOSE DEHYDROGENASE