S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE Chemical Properties

Melting point:

83-86 °C (lit.)

Boiling point:

354.3±31.0 °C(Predicted)

Density 

1.42±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

Sensitive 

Hygroscopic

InChI

1S/C6H6O4S/c1-3(7)11-4-2-5(8)10-6(4)9/h4H,2H2,1H3

InChIKey

AHTFMWCHTGEJHA-UHFFFAOYSA-N

SMILES

CC(=O)SC1CC(=O)OC1=O

CAS DataBase Reference

6953-60-2(CAS DataBase Reference)

EPA Substance Registry System

Ethanethioic acid, S-(tetrahydro-2,5-dioxo-3-furanyl) ester (6953-60-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

TSCA 

TSCA listed

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

• Language:English Provider:SigmaAldrich

S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE Usage And Synthesis

Uses

S-Acetylmercaptosuccinic anhydride is an amine reactive reagent, containing a sulfhydryl group. The anhydride region opens up, when attacked by an amine nucleophile, forming amine linkage. However, during this ring opening reaction, a free carboxylate group is formed rendering the molecule negatively charged. Activity to proteins and conformation of the molecule us affected by the charge reversal.

General Description

S-Acetylmercaptosuccinic anhydride is an amine reactive reagent, containing a sulfhydryl group. The anhydride region opens up, when attacked by an amine nucleophile, forming amine linkage. However, during this ring opening reaction, a free carboxylate group is formed rendering the molecule negatively charged. Activity to proteins and conformation of the molecule us affected by the charge reversal.

S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE(6953-60-2)Related Product Information

• 2-Mercaptobutyric acid
• S-N-PROPYL THIOACETATE
• Valeric acid
• Thioacetic acid
• Methyl thioglycolate
• METHYL (METHYLTHIO)ACETATE
• 3-Methylthiopropanol
• 2-Butanethiol
• 3-(Ethylthio)butanal
• 3-(Methylthio)propionaldehyde
• SEC-BUTYL METHYL SULFIDE
• (METHYLTHIO)ACETIC ACID
• (ETHYLTHIO)ACETIC ACID
• METHYL 2-(METHYLTHIO)PROPIONATE
• Ethyl 2-hydroxyethyl sulfide
• ETHYL (METHYLTHIO)ACETATE
• Methyl 3-mercaptopropionate
• ethyl ethanethioate