Basic information Safety Supplier Related
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Premarin

Basic information Safety Supplier Related

Premarin Basic information

Product Name:
Premarin
Synonyms:
  • conestron
  • conjes
  • conjugatedequineestrogen
  • conjugatedestrogenichormones
  • conjutabs
  • equigyne
  • estratab
  • estrifol
CAS:
12126-59-9
MF:
C18H19NaO5S
MW:
370.4
EINECS:
235-199-5
Product Categories:
  • Steroids
Mol File:
12126-59-9.mol
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Premarin Chemical Properties

CAS DataBase Reference
12126-59-9(CAS DataBase Reference)
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Premarin Usage And Synthesis

Description

Conjugated estrogens generally occur as butter-colored powders that are soluble in water. The sodiumequilin sulfate component is unstable to light and air.Piperazine estrone sulfate occurs as a white to yellowishwhite crystalline powder that is slightly soluble in water.Piperazine estrone sulfate melts at 245℃ with decomposition. Conjugated estrogens are naturally occurring substances excreted in the urine of pregnant mares; piperazineestrone sulfate is not known to occur naturally.

Chemical Properties

Almost white or brownish, amorphous powder.

Chemical Properties

Conjugated estrogens generally occur as butter-colored powders

Uses

Conjugated Estrogen is a mixture of estrogen derivatives-mostly estrone and equilin sulfate.

Definition

ChEBI: Equilin sodium sulfate is a steroid sulfate. It is functionally related to an equilin.

Safety Profile

Suspected human carcinogen producing tumors of the vascular system and liver. Human reproductive effects: changes in female fertility. When heated to decomposition it emits toxic fumes of NazO. See also indvidual components.

Potential Exposure

Conjugated estrogens are naturally occurring substances excreted in the urine of pregnant mares; piperazine estrone sulfate is not known to occur naturally. Conjugated estrogens are used to treat symptoms of the climacteric, vulvae dystrophies; female hypogonadism; and dysfunctional uterine bleeding. They also are used for treatment following: ovariectomy, for chemotherapy of mammary cancer and prostate carcinogema; and for prevention of postpartum breast engorgement. In addition, conjugated estrogens have been found in cosmetic preparations

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. A regulated, marked area should be establishedwhere this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required. UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials. PGIII.

Incompatibilities

Estrogens are Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid chlorides, and acid anhydrides.

Waste Disposal

It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged, and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator

PremarinSupplier

Xinjiang Xinzi source biopharmaceutical limited liability company Gold
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(+86)-0991-4320446
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Email
waley188@sohu.com
Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Email
sales@sunlidabio.com
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163