Basic information Safety Supplier Related

L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE

Basic information Safety Supplier Related

L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE Basic information

Product Name:
L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
Synonyms:
  • Pyr-RTKR-AMC
  • PYROGLU-ARG-THR-LYS-ARG-7-AMIDO-4-METHYLCOUMARIN
  • PYR-ARG-THR-LYS-ARG-MCA
  • PGLU-ARG-THR-LYS-ARG 7-AMIDO-4-METHYLCOUMARIN
  • L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
  • L-Argininamide, 5-oxo-L-prolyl-L-arginyl-L-threonyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
  • 50:PN:WO0042071 FIGURE:18 claimed protein
  • pGlu-Arg-Thr-Lys-Arg-MCA
CAS:
155575-02-3
MF:
C37H57N13O9
MW:
827.93
Mol File:
155575-02-3.mol
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L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE Chemical Properties

Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
−20°C
pka
12.47±0.20(Predicted)
Sequence
{Pyr}-Arg-Thr-Lys-{Arg-AMC}
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Safety Information

WGK Germany 
3

MSDS

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L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE Usage And Synthesis

Uses

Pyr-Arg-Thr-Lys-Arg-AMC is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors[1].

References

[1] Neugebauer WA, et al. C-terminal amidation on aryl hydrazine resin. Adv Exp Med Biol. 2009;611:371-2. DOI:10.1007/978-0-387-73657-0_164

L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDESupplier

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