R-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN
R-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN Basic information
- Product Name:
- R-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN
- Synonyms:
-
- R-Licarbazepine
- Licarbazepine Impurity 1(Licarbazepine R-Isomer)
- (10R)-10,11-DIHYDRO-10-HYDROXY CARBAMAZEPINE
- R-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN
- R-(-)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide,R-MHD,CGP13698
- (R)-10-Monohydroxy-dihydro-carbamazepine
- (10R)-
- (R)-10-Monohydroxy-10,11-dihydro CarbaMazepine
- CAS:
- 104746-03-4
- MF:
- C15H14N2O2
- MW:
- 254.28
- Product Categories:
-
- Heterocycles
- Intermediates & Fine Chemicals
- Chiral Reagents
- Metabolites
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 104746-03-4.mol
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R-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN Chemical Properties
- Melting point:
- 190-192°C
- Boiling point:
- 431.3±55.0 °C(Predicted)
- Density
- 1.336±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
- form
- Solid
- pka
- 13.75±0.20(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 104746-03-4
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R-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
An optically active metabolite of carbamazepine. ee=98% [a]d=-193 (C=1, pyridine
Uses
A metabolite of Eslicarbazepine acetate, (BIA 2-093) a novel central nervous system drug.
Uses
(R)-10-Monohydroxy-10,11-dihydro Carbamazepine is the metabolite of Oxcarbazepine (OXC) and Eslicarbazepine acetate, (BIA 2-093, ESL), novel central nervous system drugs. ee=98% [α]d=-193 (C=1, py ridine)
Definition
ChEBI: (R)-MHD is a dibenzooxazepine.
R-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPINSupplier
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