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10,11-DIHYDROCARBAMAZEPINE

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10,11-DIHYDROCARBAMAZEPINE Basic information

Product Name:
10,11-DIHYDROCARBAMAZEPINE
Synonyms:
  • f)azepine-5-carboxamide,10,11-dihydro-5h-dibenz(
  • 10,11-DIHYDRO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE
  • 10,11-DIHYDROCARBAMAZEPINE
  • 10,11-Dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
  • 10,11-Dihydro5H-dibenzo[b,f]azepine-5-carboxamide
  • 10,11-Dihydrocarbamazepine,99%
  • 5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
  • 10,11-Dihydrocarbamazepine,10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide
CAS:
3564-73-6
MF:
C15H14N2O
MW:
238.28
EINECS:
222-649-0
Product Categories:
  • Amines, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Amines
  • Heterocycles
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
3564-73-6.mol
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10,11-DIHYDROCARBAMAZEPINE Chemical Properties

Melting point:
205-210 °C(lit.)
Boiling point:
394.5±52.0 °C(Predicted)
Density 
1.232±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
dichloromethane: soluble2.5%, clear, colorless
form 
Solid
pka
14.07±0.20(Predicted)
color 
White to Off-White
Water Solubility 
Soluble in dichloromethane. Insoluble in water.
BRN 
196969
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-42/43
Safety Statements 
22-24/25-45-36/37
WGK Germany 
3
RTECS 
HN8300000
HS Code 
29339900

MSDS

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10,11-DIHYDROCARBAMAZEPINE Usage And Synthesis

Chemical Properties

white crystals or needles

Uses

A dihydro impurity of Carbamazepine (C175840)

Uses

10,11-Dihydrocarbamazepine is used as internal standard during simultaneous determination of carbamazepine and its active metabolite in plasma by liquid chromatography. It can be used in chemiluminescence method for determination of carbamazepine.

General Description

10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug used in the treatment of epilepsy. Single-crystal structure of new dimer-based polymorph of 10,11-dihydrocarbamazepine has been investigated.

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