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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Forensic and veterinary standards >  1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE

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1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Basic information

Product Name:
1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
Synonyms:
  • CARBAMAZEPINE 10,11-EPOXIDE
  • 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
  • 1A,10BETA-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
  • 10,11-epoxycarbamazepine
  • 1a,10b-dihydro-6h-dibenz(b,f)oxiren(d)azepine-6-carboxamide
  • carbamazepine10,11-oxide
  • carbamazepineepoxide
  • 10,11-Dihydro-10,11-epoxy-5H-dibenzo[b,f]azepine-5-carboxamide
CAS:
36507-30-9
MF:
C15H12N2O2
MW:
252.27
EINECS:
641-693-5
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Aromatics
  • Heterocycles
Mol File:
36507-30-9.mol
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1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Chemical Properties

Melting point:
204-206°C
Boiling point:
390.2±52.0 °C(Predicted)
Density 
1.377±0.06 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
-20°C
solubility 
Chloroform (Slightly), DMSO (Slightly)
pka
13.91±0.20(Predicted)
color 
White
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Safety Information

Hazard Codes 
Xn,N,T,F
Risk Statements 
22-36/37/38-51/53-39/23/24/25-23/24/25-11
Safety Statements 
26-36-61-45-36/37-16-7
RIDADR 
2811
WGK Germany 
3
RTECS 
HQ4430000
HazardClass 
6.1(b)
PackingGroup 
III

MSDS

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1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Usage And Synthesis

Chemical Properties

White Solid

Uses

A metabolite of Carbamazepine (C175840). Representative lots contained 1-2% carbamazepine by HPLC.

Uses

A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.

Uses

A metabolite of Carbamazepine. Representative lots contained 1-2% carbamazepine by HPLC

Definition

ChEBI: An epoxide and metabolite of carbamazepine.

General Description

Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine.

Biochem/physiol Actions

First metabolite of carbamazepine

1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDESupplier

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