Chlorobutanol Chemical Properties

Flash point:

100 °C

storage temp. 

Sealed in dry,Room Temperature

Odor

camphoraceous odor

CAS DataBase Reference

1320-66-7(CAS DataBase Reference)

EPA Substance Registry System

Butanol, chloro- (1320-66-7)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

26-36/37/39

Hazardous Substances Data

1320-66-7(Hazardous Substances Data)

MSDS

• Language:English Provider:Chlorobutanol

Chlorobutanol Usage And Synthesis

Chemical Properties

Crystalline solid with a camphor-like odorand taste; sublimes; mp 97°C (206°F)(hemihydrate 78°C (172°F)); bp 167°C(332°F); soluble in water and organic solvents..

Uses

Pharmaceutic aid (antimicrobial agent).

Uses

Chlorobutanol is used as a plasticizer forcellulose esters, as a preservative for hypodermic solutions, and in veterinary medicineas a mild sedative and antiseptic.

brand name

Chloretone (Parke-Davis).

Health Hazard

Chlorobutanol exhibited moderate toxicity intest animals. A lethal dose by oral intake indogs and rabbits were 238 and 213 mg/kg,respectively (NIOSH 1986). The toxic symptoms are not reported. This compound isa mild skin and eye irritant and may bemutagenic.

Clinical Use

1,1,1-Trichloro-2-methyl-2-propanol is a white crystallinesolid with a camphorlike aroma. It occurs in an anhydrousform and a hemihydrate form, both of which sublime at roomtemperature and pressure. Chlorobutanol is slightly soluble inwater and soluble in alcohol and in organic solvents.
Chlorobutanol is used as a bacteriostatic agent in pharmaceuticalsfor injection, ophthalmic use, and intranasal administration.It is unstable when heated in aqueous solution, especially at pH greater than 7. Under these conditions,chlorobutanol undergoes elimination. Solutions with a pHof approximately 5 are reasonably stable at 25°C.Chlorobutanol is stable in oils and organic solvents.

Waste Disposal

A suitable method of destruction of chlorobu tanol is the burning of its solution in a com bustible solvent in a chemical incinerator.

Chlorobutanol(1320-66-7)Related Product Information

• Potassium tert-butoxide
• CIS-2-BUTENE
• 1-BUTENE
• Ethambutol
• 3-Chloro-1,2-propanediol
• 1-Butanol
• Sodium tert-butoxide
• 2-Methyl-1-propanol
• tert-Butanol
• 4-CHLOROBUTANOL-1,4-CHLOROBUTANOL
• Dicofol
• 1,1-BIS(TRIFLUOROMETHYL)-2,2,2-TRICHLOROETHANOL
• CHLOROBUTANOL,ANHYDROUS,NF,chlorobutanol,anhydrou
• 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
• 2,2,2-TRICHLORO-1,1-DIMETHYLETHYL CHLOROFORMATE
• 1,4-DICHLORO-2-BUTANOL
• 4-Chlorobutyl acetate
• (S)-(-)-3-HYDROXY-3-METHYL-4,4,4-TRICHLOROBUTYRIC BETA-LACTONE