Basic information Safety Supplier Related

Probenazole

Basic information Safety Supplier Related

Probenazole Basic information

Product Name:
Probenazole
Synonyms:
  • 3-(allyloxy)-1,2-benzisothiazole1,1-dioxide
  • oryzaemate
  • po-20
  • probenazole (jmaf)
  • ORYZAMATE
  • PROBENAZOIE
  • 3-Allyloxy-1,2-benzoisothiazole 1,1-dioxide
  • Probenazole Standard
CAS:
27605-76-1
MF:
C10H9NO3S
MW:
223.25
Mol File:
27605-76-1.mol
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Probenazole Chemical Properties

Melting point:
136~141℃
Boiling point:
220°C (rough estimate)
Density 
1.3588 (rough estimate)
vapor pressure 
5 x 10-4 Pa (20 °C) (est.)
refractive index 
1.6500 (estimate)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
Water Solubility 
150 mg l-1
pka
-2.43±0.20(Predicted)
color 
White to Off-White
CAS DataBase Reference
27605-76-1(CAS DataBase Reference)
NIST Chemistry Reference
Probenazole(27605-76-1)
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Safety Information

HS Code 
29342000
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Probenazole Usage And Synthesis

Uses

Probenazole is used for the control of rice blast and bacterial diseases in paddy rice.

Uses

Probenazole can be used in agricultural use and biological study of preparation of nicotinamide compounds containing chiral oxazoline and application thereof as agricultural antimicrobial agent.

Definition

ChEBI: Probenazole is a member of the class of 1,2-benzothiazoles that is 1,2-benzothiazole 1,1-dioxide substituted at position 3 by an allyloxy group. A fungicide used to control rice blast. It has a role as a plant activator and an antifungal agrochemical. It is a 1,2-benzisothiazole, an aromatic ether, a sulfone and a benzothiazole fungicide. It is functionally related to a saccharin.

Metabolic pathway

Probenazole is metabolised readily in plants by hydrolytic ring opening followed by a cyclisation-induced dealkylation to form saccharin which is N-glucosylated. Saccharin may be the active metabolite of probenazole. No information on the fate of probenazole in soil or animals could be located.

Metabolism

Probenazole is taken up by the rice plants after spray or paddy application and distributed throughout the plants as parent compound or as one of its metabolites . The main metabolites of probenazole in rice are 2-sulfamoyl-allyl-benzoate, saccharin, and N-β- D-glucopyranosylsaccharin (37).

Degradation

Probenazole is a stable compound but it is subject to hydrolysis.

ProbenazoleSupplier

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