2,5-Dibromopyrazine Chemical Properties

Melting point:

45.0 to 49.0 °C

Boiling point:

234.0±35.0 °C(Predicted)

Density 

2.197

Flash point:

95℃

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

pka

-4.28±0.10(Predicted)

form 

powder to crystal

color 

White to Orange to Green

InChIKey

KIYKHEOWZLJZSB-UHFFFAOYSA-N

CAS DataBase Reference

23229-26-7

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

22-36/37/38

Safety Statements 

26-36/37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29339900

2,5-Dibromopyrazine Usage And Synthesis

Synthesis

5-bromopyrazin-2-amine (3 g, 17.241 mmol) and bromine (8.2 g, 51.729 mmol) were added to aq. HBr solution at -15° C. Aq. solution of sodium nitrite (2.97 g, 43.0103 mmol) was then added to the mixture over a period of 1 h at -10° C. keeping the internal temperature below 5° C. during addition and stirred for 1 h at 0° C. Progress of reaction was monitored by TLC. After reaction completion reaction mass neutralised with 40percent NaOH solution and extracted with diethyl ether. The organic layer was dried over sodium sulphate and concentrated under reduced pressure (below 30° C.) to yield 2,5-Dibromopyrazine (1 g, 24.4percent) as brown oil.

2,5-Dibromopyrazine(23229-26-7)Related Product Information

• 2,5-Difluorobenzoic acid
• 2,5-Dibromopyridine
• Glipizide
• Sulfachoropyrazine sodium
• Pyrazinamide
• 2,5-Dimethylthiophene
• 2,5-Dimethoxytoluene
• 2,5-Dimethylfuran
• 2,5-DIBROMO-3-METHOXYPYRAZINE
• 2,6-Dibromopyrazine
• 2-AMINO-3,5-DIBROMOPYRAZINE,3,5-DIBROMOPYRAZINE-2-YLAMINE
• methyl 3,6-dibromopyrazine-2-carboxylate
• 2,3-DIBROMOPYRAZINE
• 3,6-dibromopyrazine-2-carbaldehyde
• 3,6-dibromopyrazin-2-amine
• 2,5-Dibromopyrazine
• 3,6-Dibromopyrazine