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2-Amino-3,5-dibromopyrazine

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2-Amino-3,5-dibromopyrazine Basic information

Product Name:
2-Amino-3,5-dibromopyrazine
Synonyms:
  • 2-AMINO-3,5-DIBROMOPYRAZINE
  • 3,5-DIBROMOPYRAZIN-2-YLAMINE
  • 3,5-DIBROMOPYRAZINE-2-YLAMINE
  • 3,5-DIBROMOPYRAZIN-2-AMINE
  • 2-AMINO-3,5-DIBROMOPYRAZIN
  • 3,5-dibromo-2-Pyrazinamine
  • 3,5-dibromo-2-aminopyrazine
  • 2-Amino-3,5-dibromopyrazine ,98%
CAS:
24241-18-7
MF:
C4H3Br2N3
MW:
252.89
Product Categories:
  • Chloropyrazines, etc.
  • Pyrazine
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • PyrazinesHeterocyclic Building Blocks
  • pharmacetical
  • Pyrazines
  • amine| alkyl bromide
Mol File:
24241-18-7.mol
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2-Amino-3,5-dibromopyrazine Chemical Properties

Melting point:
114-117 °C (lit.)
Boiling point:
294.6±35.0 °C(Predicted)
Density 
2.287±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
soluble in Methanol
pka
0.81±0.10(Predicted)
form 
Powder
color 
Yellow to brown
InChIKey
DTLBKXRFWUERQN-UHFFFAOYSA-N
CAS DataBase Reference
24241-18-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-37/38-41
Safety Statements 
26-36/39
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29339900

MSDS

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2-Amino-3,5-dibromopyrazine Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

2-Amino-3,5-dibromopyrazine is used in the preparation of conjugated polymers for neurotoxin detection. 2-Amino-3,5-dibromopyrazine is an intermediate in the preparation of rho kinase (ROCK) inhibitor s.

Uses

2-Amino-3,5-dibromopyrazine may be used in the synthesis of:

  • 2-amino-5-bromopyrazin-3-thiol
  • 2-amino-3,5-bis(p-methoxyphenyl)-1,4-pyrazine
  • 3,7-dihydroimidazo[1,2a]pyrazine-3-ones

General Description

2-Amino-3,5-dibromopyrazine can be synthesized from 2-aminopyrazine via bromination using N-bromosuccinimide (NBS). It reacts with sodium dicyanocuprate to form a mixture of mono and dicyanation products. The formation of 2-aminothiazolopyrazines by reacting 2-amino-3,5-dibromopyrazine with isothiocyanates has been reported.

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