2'-Deoxyguanosine-5'-triphosphate trisodium salt Chemical Properties

Melting point:

>0°C

storage temp. 

-20°C

solubility 

PBS (pH 7.2): 5 mg/mL

form 

solid

color 

colorless

InChI

InChI=1/C10H16N5O13P3.Na.H/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17);;/t4-,5+,6+;;/s3

InChIKey

IWGGLKOTEOCWQP-BQHLMXRXSA-K

SMILES

O=C1NC(N)=NC2N([C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O3)C=NC1=2.[NaH] |&1:8,10,12,r|

CAS DataBase Reference

93919-41-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

22-26-36-37/39

WGK Germany 

3

F 

10-21

HS Code 

29349990

MSDS

• Language:English Provider:2'-Deoxyguanosine 5'-(tetrahydrogen triphosphate) trisodium salt

2'-Deoxyguanosine-5'-triphosphate trisodium salt Usage And Synthesis

Description

2′-Deoxyguanosine 5′-triphosphate (dGTP) is made of a guanine nucleobase attached to deoxyribose and a 5′-hydroxyl on the sugar linked to a chain of three phosphate residues. It is used by the cells for the synthesis of DNA with the help of DNA polymerase.

Chemical Properties

White amorphous powder

Uses

2′-Deoxyguanosine 5′-triphosphate trisodium salt is utilized for methods such as DNA sequencing, PCR and other DNA polymerase based DNA synthesis and repair techniques.

General Description

dGTP, PCR Grade, is a 100 mM clear, colorless solution of the sodium salt (pH 8.3). PCR Grade nucleotides from Roche are specially manufactured and purified to the highest possible chemical purity. PCR Grade nucleotides contain at least 99% of the relevant deoxynucleoside-triphosphate (dNTP) and less than 0.9% deoxynucleoside-diphosphate (dNDP).

Biochem/physiol Actions

2′-Deoxyguanosine 5′-triphosphate is used in vivo synthesis for the synthesis of DNA via DNA polymerases.

storage

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

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