Basic information Safety Supplier Related

Guanosine 5'-triphosphate trisodium salt

Basic information Safety Supplier Related

Guanosine 5'-triphosphate trisodium salt Basic information

Product Name:
Guanosine 5'-triphosphate trisodium salt
Synonyms:
  • Guanosine 5′-triphosphate sodium salt hydrate
  • GUANOSINE-5'-TRIPHOSPHATE TETRASODIUM SALT
  • 5'-triphosphate trisodium salt
  • GTP, trisodium salt, ≥96%(HPLC)
  • guanosine 5'-triphosphate sodium salt solution
  • Guanosine 5'-(tetrahydrogen triphosphate), trisodium salt
  • GUANOSINE 5'-TRIPHOSPHATE SODIUM 100 MM SOLUTION MO
  • GUANOSINE 5'-TRIPHOSPHATE SODIUM*PREPARE D ENZYMATIC
CAS:
36051-31-7
MF:
C10H17N5NaO14P3
MW:
547.18
EINECS:
252-847-2
Product Categories:
  • Pharmaceutical
Mol File:
36051-31-7.mol
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Guanosine 5'-triphosphate trisodium salt Chemical Properties

Melting point:
254 - 256°C
storage temp. 
-20°C
solubility 
H2O: 50 mg/mL
form 
powder
color 
white
optical activity
[α]20/D 24±2°, c = 1% in 0.5 M Na2HPO4
BRN 
4113439
Stability:
Hygroscopic
CAS DataBase Reference
36051-31-7(CAS DataBase Reference)
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Safety Information

Hazard Codes 
T
Risk Statements 
23/24/25-36/37/38-39/23/24/25
Safety Statements 
26-36/37/39-45
WGK Germany 
3
10-21
HS Code 
29349990
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Guanosine 5'-triphosphate trisodium salt Usage And Synthesis

Uses

Guanosine 5′-triphosphate sodium salt solution has been used for reconstituting transducin during purification of transducin.

General Description

GTP is supplied as the disodium salt in crystal form.

Biochem/physiol Actions

GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

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