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GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE

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GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Basic information

Product Name:
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
Synonyms:
  • Cyclic 3',5'-guanylic acid
  • Cyclic guanosine phosphate
  • Guanosine 3',5'-phosphoric acid
  • Guanosine cyclic 3',5'-monophosphate
  • 3',5'-Cyclic guanosine Monophosphate
  • 3',5'-cGMPH
  • Guanosine 3′,5′-cyclic monophosphate,cGMP, cyclic GMP
  • Guanosine 3',5'-Monophosphate
CAS:
7665-99-8
MF:
C10H12N5O7P
MW:
345.21
EINECS:
231-641-6
Product Categories:
  • Alphabetic
  • Analytical Standards
  • Nucleotides&Nucleosides
  • Food&Beverage Standards
  • GChromatography
Mol File:
7665-99-8.mol
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GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Chemical Properties

Melting point:
>242°C (dec.)
Density 
2?+-.0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
1% sodium bicarbonate: 50 mg/mL
form 
powder
pka
1.03±0.60(Predicted)
color 
white
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-26-36
WGK Germany 
3
HS Code 
29349990
Toxicity
The product formed by the guanylate cyclase enzymes from GTP. It is a cellular “second messenger,” participating in the regulation of many intracellular events. Toxicants (e.g., nitroprusside) may cause physiological changes by interfering with aspects of cyclic GMP metabolism.

MSDS

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GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Usage And Synthesis

Chemical Properties

White powder

Uses

Guanosine 3'',5''-Cyclic Monophosphate is an intracellular second messenger which are involved in the transduction of a diverse array of stimuli, mediating metabolic and growth regulation.

Definition

ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP.

Biochem/physiol Actions

An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATESupplier

Hangzhou Meiya Pharmaceutical Co.,ltd. Gold
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021-33686691 18001850931;
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lijh@meiyapharm.com
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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Hongene Biotech Corporation
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021-64757213
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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