ChemicalBook > Product Catalog > Biochemical Engineering > Nucleoside drugs > Nucleoside Intermediates > GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Basic information
- Product Name:
- GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
- Synonyms:
-
- Cyclic 3',5'-guanylic acid
- Cyclic guanosine phosphate
- Guanosine 3',5'-phosphoric acid
- Guanosine cyclic 3',5'-monophosphate
- 3',5'-Cyclic guanosine Monophosphate
- 3',5'-cGMPH
- Guanosine 3′,5′-cyclic monophosphate,cGMP, cyclic GMP
- Guanosine 3',5'-Monophosphate
- CAS:
- 7665-99-8
- MF:
- C10H12N5O7P
- MW:
- 345.21
- EINECS:
- 231-641-6
- Product Categories:
-
- Alphabetic
- Analytical Standards
- Nucleotides&Nucleosides
- Food&Beverage Standards
- GChromatography
- Mol File:
- 7665-99-8.mol
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GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Chemical Properties
- Melting point:
- >242°C (dec.)
- Density
- 2?+-.0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- 1% sodium bicarbonate: 50 mg/mL
- form
- powder
- pka
- 1.03±0.60(Predicted)
- color
- white
- Stability:
- Hygroscopic
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-26-36
- WGK Germany
- 3
- HS Code
- 29349990
- Toxicity
- The product formed by the guanylate cyclase enzymes from GTP. It is a cellular “second messenger,” participating in the regulation of many intracellular events. Toxicants (e.g., nitroprusside) may cause physiological changes by interfering with aspects of cyclic GMP metabolism.
MSDS
- Language:English Provider:SigmaAldrich
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GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Usage And Synthesis
Chemical Properties
White powder
Uses
Guanosine 3'',5''-Cyclic Monophosphate is an intracellular second messenger which are involved in the transduction of a diverse array of stimuli, mediating metabolic and growth regulation.
Definition
ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP.
Biochem/physiol Actions
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATESupplier
Hangzhou Meiya Pharmaceutical Co.,ltd. Gold
- Tel
- 021-33686691 18001850931;
- lijh@meiyapharm.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Hongene Biotech Corporation
- Tel
- 021-64757213
- info@hongene.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky(shanghai)International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
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