(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE
(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE Basic information
- Product Name:
- (3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE
- Synonyms:
-
- RP 67580
- (3aR,7aR)-Octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-4H-isoindol
- 4H-Isoindol-4-one, octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-, (3ar,7ar)-
- 4H-Isoindol-4-one, octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-, (3ar-cis)-
- 7,7-Diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one
- (3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE
- Rp 68651
- (3aR,7aR)-2-(1-Imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenylhexahydro-1H-isoindol-4(2H)-one
- CAS:
- 135911-02-3
- MF:
- C29H30N2O2
- MW:
- 438.56
- Product Categories:
-
- Tachykinin receptor
- Mol File:
- 135911-02-3.mol
More
Less
(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE Chemical Properties
- storage temp.
- Store at +4°C
- solubility
- Soluble to 100 mM in ethanol and to 50 mM in DMSO
- form
- Powder
More
Less
(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE Usage And Synthesis
Uses
RP 67580 is a neurokinin-1 receptor (NK1) antagonist.
Biological Activity
Potent and selective tachykinin NK 1 receptor antagonist (K i values are 2.9 nM and > 10 μ M for rat NK 1 , and rat NK 2 and NK 3 receptors respectively). Displays higher affinity at rat and mouse than human receptors. Antinociceptive in vivo , possibly partly via inhibition of calcium channels.
storage
Store at -20°C
(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
BOC Sciences
- Tel
- info@bocsci.com
MedBioPharmaceutical Technology Inc
- Tel
- 021-69568360 18916172912
- order@med-bio.cn