Basic information Safety Supplier Related

THIP HYDROCHLORIDE

Basic information Safety Supplier Related

THIP HYDROCHLORIDE Basic information

Product Name:
THIP HYDROCHLORIDE
Synonyms:
  • THIP HYDROCHLORIDE
  • 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3(2h)-onehydrate
  • 4-c)pyridin-3(2h)-one,4,5,6,7-tetrahydro-isoxazolo(hydrate
  • gaboxadol
  • 4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL
  • 4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL HYDROCHLORIDE
  • 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one
  • THIP
CAS:
64603-91-4
MF:
C6H8N2O2
MW:
140.14
EINECS:
264-963-0
Product Categories:
  • GABA/Glycine receptor
Mol File:
64603-91-4.mol
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THIP HYDROCHLORIDE Chemical Properties

Melting point:
242-244° (dec)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
ethanol: 0.91 mg/mL
pka
pKa (water, 25°): 4.44 ±0.03; 8.48 ±0.04
form 
solid
color 
white
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
NY3396800

MSDS

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THIP HYDROCHLORIDE Usage And Synthesis

Description

Gaboxadol HCl (64603-91-4) is a GABA-A receptor agonist. Hypnotic agent.

Uses

GABAa agonist, GABAc antagonist

Definition

ChEBI: 4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3-ol is an oxazole.

Biological Activity

Systemically active GABA A receptor agonist and GABA C receptor antagonist. Displays antinociceptive, anticonvulsant and sedative effects. Hypnotic agent that enhances delta activity within non-REM sleep in rats.

References

1) Meera et al. (2011), Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptors; J. Neurophysiol., 106 2057

THIP HYDROCHLORIDESupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
LGM Pharma
Tel
1-(800)-881-8210
Email
inquiries@lgmpharma.com
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Email
info@sagechem.com
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
021-50430803 18017383231
Email
983544897@qq.com
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Email
info@tsbiochem.com
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