p-Tolyl isocyanate Chemical Properties

Melting point:

155-156 °C(Solv: acetonitrile (75-05-8); hexane (110-54-3))

Boiling point:

70-72 °C/10 mmHg (lit.)

Density 

1.056 g/mL at 25 °C (lit.)

vapor pressure 

75.5Pa at 25℃

refractive index 

n20/D 1.531(lit.)

Flash point:

152 °F

storage temp. 

2-8°C

form 

Liquid

color 

Clear slightly brown

Water Solubility 

7.5g/L at 20℃

Sensitive 

Moisture Sensitive

BRN 

471494

InChIKey

MGYGFNQQGAQEON-UHFFFAOYSA-N

LogP

1.39

CAS DataBase Reference

622-58-2(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1-isocyanato-4-methyl-(622-58-2)

EPA Substance Registry System

p-Tolyl isocyanate (622-58-2)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38-42

Safety Statements 

23-26-45-36/37/39

RIDADR 

2206

WGK Germany 

3

RTECS 

DA3681666

F 

21

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29299010

MSDS

• Language:English Provider:4-Methylphenyl isocyanate
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

p-Tolyl isocyanate Usage And Synthesis

Chemical Properties

CLEAR SLIGHTLY BROWN LIQUID

Uses

p-Tolyl isocyanate was used to study the catalytic role of supported Rhodium(I) complex toward the reductive carbonylation of nitrobenzene in DMF medium.

Definition

ChEBI: An isocyanate comprising a benzene core with isocyanato and methyl substituents para to each other.

General Description

p-Tolyl isocyanate reacts with human serum albumin to form antigen which helps in detecting IgE antibodies in workers hypersensitive to toluene diisocyanate.

Hazard

A Poison by inhalation. Moderately toxic by ingestion.

p-Tolyl isocyanate(622-58-2)Related Product Information

• Isocyanatocyclohexane
• Chlorosulfonyl isocyanate
• 1,4-PHENYLENE DIISOTHIOCYANATE
• Phenyl isothiocyanate
• Propyl isocyanate
• Sodium p-toluenesulfinate
• p-Toluenesulfonyl Isocyanate
• ISOCYANATE
• 4-Chloro-α,α,α-trifluoro-m-tolyl isocyanate
• 4-TOLYL ISOCYANATE
• 4-Chloro-2-isocyanatotoluene
• 4-Methoxy-o-tolyl isocyanate
• à,à,à-trifluoro-p-tolyl isocyanate,ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLYL ISOCYANATE,α,α,α-Trifluoro-p-tolyl isocyanate
• 6-Methoxy-m-tolyl isocyanate
• O-TOLYL ISOCYANATE, 99+%,O-TOLYL ISOCYANATE,2-TOLYL ISOCYANATE
• 2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
• 3-chloro-p-tolyl isocyanate
• TOLUALDEHYDES