Chlorosulfonyl isocyanate Chemical Properties

Melting point:

-44 °C (lit.)

Boiling point:

107 °C (lit.)

Density 

1.626 g/mL at 25 °C (lit.)

vapor pressure 

5.57 psi ( 20 °C)

refractive index 

n20/D 1.447(lit.)

Flash point:

>110°C

storage temp. 

2-8°C

solubility 

Chloroform (Slightly, Heated)

form 

Crystals, Crystalline Powder or Granules

Specific Gravity

1.626 (20℃)

color 

White

Water Solubility 

reacts violently exothermic

BRN 

1237247

CAS DataBase Reference

1189-71-5(CAS DataBase Reference)

EPA Substance Registry System

Sulfuryl chloride isocyanate (1189-71-5)

Safety Information

Hazard Codes 

C

Risk Statements 

14-22-34-42-20/22

Safety Statements 

23-26-30-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

10-21-19

HazardClass 

8

PackingGroup 

II

HS Code 

28510080

Toxicity

LD50 orally in Rabbit: 640 mg/kg

MSDS

• Language:English Provider:N-Carbonylsulfamyl chloride
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

Chlorosulfonyl isocyanate Usage And Synthesis

Chemical Properties

Clear liquid, colourless

Uses

Chlorosulfonyl isocyanate, a highly reactive chemical for chemical synthesis, is used as an intermediate used for production of antibiotics (Cefuroxime, penems), polymers as well as agrochemicals. Product Data Sheet

Uses

Employed in a regio- and diastereoselective introduction of a protected amino group in a synthesis of chiral, polyhydroxylated piperidines. Generation of ureas from amino groups in a synthesis of benzimidazolones.

General Description

Chlorosulfonyl isocyanate reacts with hydrocarbon alkenes via stepwise dipolar pathway to give N-chlorosulfonyl-β-lactams.

Chlorosulfonyl isocyanate(1189-71-5)Related Product Information

• Propyl isocyanate
• Thionyl chloride
• Tosylmethyl isocyanide
• BENZOYL ISOCYANATE
• Hexyl isocyanate
• SULFURYL FLUORIDE
• Sulfosulfuron
• p-Toluenesulfonyl Isocyanate
• Polyvinyl chloride
• Choline chloride
• Ammonium chloride
• Phenylmethylsulfonyl fluoride
• Potassium chloride
• Benzyl isocyanate
• Calcium chloride
• Sodium chloride
• CHLOROMETHYL PHENYL SULFIDE
• 3-Isocyanatopropyltriethoxysilane