H-VAL-PRO-LEU-OH Chemical Properties

Boiling point:

575.9±50.0 °C(Predicted)

Density 

1.157±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Store in freezer, under -20°C

form 

White lyophilized powder.

pka

3.71±0.21(Predicted)

color 

White to off-white

H-VAL-PRO-LEU-OH Usage And Synthesis

Uses

Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue[1][2].

Definition

ChEBI: Val-Pro-Leu is an oligopeptide.

References

[1] Rahfeld J, et al. Are diprotin A (Ile-Pro-Ile) and diprotin B (Val-Pro-Leu) inhibitors or substrates of dipeptidyl peptidase IV? Biochim Biophys Acta. 1991 Jan 29;1076(2):314-6. DOI:10.1016/0167-4838(91)90284-7
[2] Hatanaka T, et al. Inhibitory effect of collagen-derived tripeptides on dipeptidylpeptidase-IV activity. J Enzyme Inhib Med Chem. 2014 Dec;29(6):823-8. DOI:10.3109/14756366.2013.858143

H-VAL-PRO-LEU-OH(90614-49-6)Related Product Information

• DIPROTIN A
• AC-GLY-LEU-OH
• 2-(Aminomethyl)-1-ethylpyrrolidine
• Gly-Gly-Leu
• (S)-2-AMINO-3-METHYL-1-(PYRROLIDIN-1-YL)BUTAN-1-ONE
• H-ALA-PRO-GLY-OH
• H-GLY-ALA-LEU-OH
• H-GLY-PRO-GLY-OH
• H-VAL-PRO-LEU-OH
• H-VAL-GLY-GLY-OH
• H-ALA-PRO-ALA-OH
• H-ALA-PRO-LEU-OH
• H-GLY-PRO-ALA-OH
• ESTHPRISSEVHIPL
• H-PRO-LEU-OH
• ETHYL[(1-PROPYLPYRROLIDIN-2-YL)METHYL]AMINE
• N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-1-PROPANAMINE
• (1-BUTYL-2-PYRROLIDINYL)-N-METHYLMETHANAMINE